Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2179752..2180023 Replicon chromosome
Accession NZ_CP045863
Organism Escherichia coli O157:H7 strain ATCC 43890

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2179790..2179893 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2179752..2180023 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GIX96_RS10970 2176909..2178348 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GIX96_RS10975 2178466..2178702 + 237 WP_001295499.1 DUF1480 family protein -
GIX96_RS10980 2178807..2178998 + 192 WP_001296140.1 YebW family protein -
GIX96_RS10985 2178999..2179655 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2179752..2180023 + 272 - - Antitoxin
- 2179790..2179893 - 104 - - Toxin
GIX96_RS10990 2180051..2180392 - 342 WP_000976483.1 YebY family protein -
GIX96_RS10995 2180405..2181277 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
GIX96_RS11000 2181281..2181655 - 375 WP_000168751.1 CopC domain-containing protein YobA -
GIX96_RS11005 2181794..2182024 + 231 WP_000916763.1 DNA polymerase III subunit theta -
GIX96_RS11010 2182126..2182782 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
GIX96_RS11015 2182806..2183468 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T142873 NZ_CP045863:c2179893-2179790 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT142873 NZ_CP045863:2179752-2180023 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References