Detailed information of TA system TA142856

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazF-chpS/PRK09907-MazE
• Location: 1732384..1732967
• Replicon: chromosome
• Accession: NZ_CP045857
• Organism: Shewanella chilikensis strain DC57

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: -
• Locus tag: GII14_RS08025
• Protein ID: WP_165564826.1
• Coordinates: 1732638..1732967 (+)
• Length: 110 a.a.

Antitoxin (Protein)

• Gene name: chpS
• Uniprot ID: -
• Locus tag: GII14_RS08020
• Protein ID: WP_165564825.1
• Coordinates: 1732384..1732638 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GII14_RS08000	1728666..1730149	+	1484	Protein_1535	IS3 family transposase	-
GII14_RS08005	1730170..1730403	+	234	WP_165564823.1	hypothetical protein	-
GII14_RS08010	1730435..1731559	-	1125	WP_165564824.1	IS630 family transposase	-
GII14_RS08015	1731633..1731872	+	240	WP_165564707.1	MarR family transcriptional regulator	-
GII14_RS08020	1732384..1732638	+	255	WP_165564825.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
GII14_RS08025	1732638..1732967	+	330	WP_165564826.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
GII14_RS08030	1732986..1733426	+	441	WP_165564827.1	hypothetical protein	-
GII14_RS08035	1733872..1734852	+	981	WP_165564818.1	IS5-like element ISEc68 family transposase	-
GII14_RS08040	1735152..1736276	-	1125	WP_165564824.1	IS630 family transposase	-
GII14_RS08045	1736350..1736589	+	240	WP_165564707.1	MarR family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1712400..1804986	92586
	-	inside	IScluster/Tn	-	-	1722433..1747075	24642

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (3-107)

Antitoxin

• SpoVT-AbrB domain (6-45)

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 12012.95 Da
• Isoelectric Point: 9.6874

>T142856 WP_165564826.1 NZ_CP045857:1732638-1732967 [Shewanella chilikensis]
MSYTPRRGDIVWVDFDPSAGHEQAHHRPALVLSPEPFNKQIQLALVAPITSRVRGHGFEVAVDTDKTKGVVLCQQVKTID
YAARGIKFIEKAPVAVLNEVLAKVRVLVS

Nucleotide

• Length: 330 bp

>T142856 NZ_CP060885:2730920-2731027 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGTGTAACCGGAAGTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 8992.24 Da
• Isoelectric Point: 4.3189

>AT142856 WP_165564825.1 NZ_CP045857:1732384-1732638 [Shewanella chilikensis]
MQTSIKKWGNSAGAIIPAAVLKKAGFGMGDQVEIEVVQGRIVMSPATPTFTLEELLNVSPKGSFELDSEDNQWLSSSPVG
KEEI

Nucleotide

• Length: 255 bp

>AT142856 NZ_CP060885:c2730867-2730806 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT