142855

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 1417426..1418068 Replicon chromosome
Accession NZ_CP045857
Organism Shewanella chilikensis strain DC57

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag GII14_RS06610 Protein ID WP_165564715.1
Coordinates 1417646..1418068 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID A0A7X5Z2N1
Locus tag GII14_RS06605 Protein ID WP_028779782.1
Coordinates 1417426..1417665 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GII14_RS06580 1413108..1413935 + 828 WP_039034196.1 prolipoprotein diacylglyceryl transferase -
GII14_RS06585 1413935..1414729 + 795 WP_101053477.1 thymidylate synthase -
GII14_RS06590 1414847..1416022 + 1176 WP_101053479.1 Na+/H+ antiporter NhaA -
GII14_RS06595 1416034..1416402 + 369 WP_101053628.1 hypothetical protein -
GII14_RS06600 1416419..1417327 + 909 WP_101053481.1 transcriptional activator NhaR -
GII14_RS06605 1417426..1417665 + 240 WP_028779782.1 succinate dehydrogenase assembly factor 2 Antitoxin
GII14_RS06610 1417646..1418068 + 423 WP_165564715.1 hypothetical protein Toxin
GII14_RS06615 1418085..1419695 - 1611 WP_101053485.1 L-aspartate oxidase -
GII14_RS06620 1419895..1420473 + 579 WP_025010551.1 RNA polymerase sigma factor RpoE -
GII14_RS06625 1420498..1421118 + 621 WP_165564716.1 anti-sigma factor -
GII14_RS06630 1421128..1422060 + 933 WP_165564717.1 MucB/RseB C-terminal domain-containing protein -
GII14_RS06635 1422071..1422550 + 480 WP_165564718.1 SoxR reducing system RseC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-135)

Antitoxin

Flavinator of succinate dehydrogenase

(5-75)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16244.77 Da        Isoelectric Point: 7.5563

>T142855 WP_165564715.1 NZ_CP045857:1417646-1418068 [Shewanella chilikensis]
VAGQRHRFQLSSSFSQYLSLTVLAAVCLSSFLAWPALDYPFYLSFKYLCLLLVLVAFGLALWRLRRWQLCFWLNELGEGQ
FEPGSSFELSGKPWVSPFVVTFTYQGEDNCGRCWLFADMFDDTDYRHLCRLLLQRSKSAN

Download         Length: 423 bp

>T142855 NZ_CP060885:2730384-2730491 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9247.74 Da        Isoelectric Point: 5.0633

>AT142855 WP_028779782.1 NZ_CP045857:1417426-1417665 [Shewanella chilikensis]
MSTPRVKWACRRGMLELDVLFQPFVEQHYETLSPEDKALFVRLLECEDPELFAWFMGHEQCPDPQLAQMVVRVRGRAAP

Download         Length: 240 bp

>AT142855 NZ_CP060885:c2730337-2730271 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7X5Z2N1

References