Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 2932371..2932972 Replicon chromosome
Accession NZ_CP045854
Organism Agrobacterium sp. MA01

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag GH983_RS14240 Protein ID WP_153762737.1
Coordinates 2932371..2932553 (+) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag GH983_RS14245 Protein ID WP_153762738.1
Coordinates 2932574..2932972 (+) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(6-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(4-124)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6643.85 Da        Isoelectric Point: 11.0889

>T142850 WP_153762737.1 NZ_CP045854:2932371-2932553 [Agrobacterium sp. MA01]
MEKDSRKIIQRLKAEGYELVSVSGSHHKLRKGGKTIIVPHPKKDLPLGTARAIAKQAGWI

Download         Length: 183 bp

>T142850 NZ_CP060885:1843792-1844043 [Escherichia coli]
ATGCGTACAATTAGTTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14659.55 Da        Isoelectric Point: 4.4008

>AT142850 WP_153762738.1 NZ_CP045854:2932574-2932972 [Agrobacterium sp. MA01]
MRYYVALVHKDLESAYGISFPDLPTVFSAADRDEDLVINAIEALRLWAEDEELPVPSSHQDIVERSDVRDELAAGAFLIR
VPLIEDDTRTVRANITMEAGTLAAIDQVAKQRGLTRSAFLASCARKEIERSA

Download         Length: 399 bp

>AT142850 NZ_CP060885:1844040-1844294 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAGTCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAGCATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References