Detailed information of TA system TA142849

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 2631145..2631815
• Replicon: chromosome
• Accession: NZ_CP045854
• Organism: Agrobacterium sp. MA01

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: GH983_RS12785
• Protein ID: WP_153762579.1
• Coordinates: 2631555..2631815 (-)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: GH983_RS12780
• Protein ID: WP_153762578.1
• Coordinates: 2631145..2631555 (-)
• Length: 137 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GH983_RS12760	2627329..2627793	+	465	WP_054148481.1	Lrp/AsnC ligand binding domain-containing protein	-
GH983_RS12765	2627973..2628665	+	693	WP_153762576.1	LuxR family transcriptional regulator	-
GH983_RS12770	2628751..2629860	-	1110	WP_153762577.1	DUF2333 family protein	-
GH983_RS12775	2629853..2631148	-	1296	WP_069043623.1	hypothetical protein	-
GH983_RS12780	2631145..2631555	-	411	WP_153762578.1	helix-turn-helix transcriptional regulator	Antitoxin
GH983_RS12785	2631555..2631815	-	261	WP_153762579.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
GH983_RS12790	2631867..2633780	-	1914	WP_153762580.1	AAA family ATPase	-
GH983_RS12795	2633783..2634934	-	1152	WP_153762581.1	hypothetical protein	-
GH983_RS12800	2635014..2636102	-	1089	WP_153762582.1	hypothetical protein	-
GH983_RS12805	2636307..2636672	-	366	WP_197277985.1	cytochrome c family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-82)

Antitoxin

• Cro/C1-type helix-turn-helix domain (76-123)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 9913.31 Da
• Isoelectric Point: 10.6564

>T142849 WP_153762579.1 NZ_CP045854:c2631815-2631555 [Agrobacterium sp. MA01]
VRDIVYSKDAIRSLNRMPANEARRIRSKVLQYAADPASLANNVKKLRDSRYHRLRIGDWRVIFREDGTVVDVVRVAARGE
AYEGEL

Nucleotide

• Length: 261 bp

>T142849 NZ_CP060885:1352296-1352694 [Escherichia coli]
ATGCTGAAATTCATGCTGGATACCAATATCTGTATTTTCACTATTAAGAATAAACCAGTACATGTCAGAGAGCGGTTTAA
CCTGAATTCTGGCCGGATGTGTATAAGTTCTGTAACATTGATGGAGCTTATCTATGGGGCAGAAAAAAGTCAGATGCCAG
AACGCAATTTGGCGGTTATTGAAGGTTTCGTATCTCGTTTGGTAGTGCTTGATTATGATAGTGCTGCTGCGACGCATACC
GGGCAAATCAGGGCCGAGCTTGCCCGGCAGGGAAGGCCTGTTGGACCTTTTGACCAGATGATAGCGGGACATGCTCGCAG
TCGCGGTTTGATTGTGGTTACCAACAATACCCGAGAGTTTGAGCGAGTGGCGGGAATCAGACTAGAAGACTGGAGCTAA

Antitoxin

Protein

• Length: 137 a.a.
• Molecular weight: 14995.94 Da
• Isoelectric Point: 4.3342

>AT142849 WP_153762578.1 NZ_CP045854:c2631555-2631145 [Agrobacterium sp. MA01]
MTIASSFTTPNGEEMIVLSRKDYEALIERIEDLEDSLAVVGFERKLAAGEEELIPAEYVNRMGEGESPIRVWRDFRGMAA
KDLAAAAGISTAYLSEIETGKKDGSVATLKAIADVLKLDLDDLYWRHEGRKVTDTA

Nucleotide

• Length: 411 bp

>AT142849 NZ_CP060885:1352069-1352296 [Escherichia coli]
ATGGAAACTACTGTATTTTTAAGTAATCGCAGTCAGGCCGTCAGATTACCGAAAGCGGTCGCTCTGCCAGAAGACGTTAA
GAAAGTAGAAATTATTGCGATTGGTCGTACAAGAATCATCACTCCCGCCGGTGAGTCCTGGGACAGTTGGTTTGATGGCG
AAAATGTGAGTGCGGATTTTATGGATATCCGTGATCAACCCGCAATGCAGGAAAGGGAATCATTTTGA