Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2631145..2631815 Replicon chromosome
Accession NZ_CP045854
Organism Agrobacterium sp. MA01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GH983_RS12785 Protein ID WP_153762579.1
Coordinates 2631555..2631815 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GH983_RS12780 Protein ID WP_153762578.1
Coordinates 2631145..2631555 (-) Length 137 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GH983_RS12760 2627329..2627793 + 465 WP_054148481.1 Lrp/AsnC ligand binding domain-containing protein -
GH983_RS12765 2627973..2628665 + 693 WP_153762576.1 LuxR family transcriptional regulator -
GH983_RS12770 2628751..2629860 - 1110 WP_153762577.1 DUF2333 family protein -
GH983_RS12775 2629853..2631148 - 1296 WP_069043623.1 hypothetical protein -
GH983_RS12780 2631145..2631555 - 411 WP_153762578.1 helix-turn-helix transcriptional regulator Antitoxin
GH983_RS12785 2631555..2631815 - 261 WP_153762579.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GH983_RS12790 2631867..2633780 - 1914 WP_153762580.1 AAA family ATPase -
GH983_RS12795 2633783..2634934 - 1152 WP_153762581.1 hypothetical protein -
GH983_RS12800 2635014..2636102 - 1089 WP_153762582.1 hypothetical protein -
GH983_RS12805 2636307..2636672 - 366 WP_197277985.1 cytochrome c family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin

Cro/C1-type helix-turn-helix domain

(76-123)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9913.31 Da        Isoelectric Point: 10.6564

>T142849 WP_153762579.1 NZ_CP045854:c2631815-2631555 [Agrobacterium sp. MA01]
VRDIVYSKDAIRSLNRMPANEARRIRSKVLQYAADPASLANNVKKLRDSRYHRLRIGDWRVIFREDGTVVDVVRVAARGE
AYEGEL

Download         Length: 261 bp

>T142849 NZ_CP060885:1352296-1352694 [Escherichia coli]
ATGCTGAAATTCATGCTGGATACCAATATCTGTATTTTCACTATTAAGAATAAACCAGTACATGTCAGAGAGCGGTTTAA
CCTGAATTCTGGCCGGATGTGTATAAGTTCTGTAACATTGATGGAGCTTATCTATGGGGCAGAAAAAAGTCAGATGCCAG
AACGCAATTTGGCGGTTATTGAAGGTTTCGTATCTCGTTTGGTAGTGCTTGATTATGATAGTGCTGCTGCGACGCATACC
GGGCAAATCAGGGCCGAGCTTGCCCGGCAGGGAAGGCCTGTTGGACCTTTTGACCAGATGATAGCGGGACATGCTCGCAG
TCGCGGTTTGATTGTGGTTACCAACAATACCCGAGAGTTTGAGCGAGTGGCGGGAATCAGACTAGAAGACTGGAGCTAA

Antitoxin


Download         Length: 137 a.a.        Molecular weight: 14995.94 Da        Isoelectric Point: 4.3342

>AT142849 WP_153762578.1 NZ_CP045854:c2631555-2631145 [Agrobacterium sp. MA01]
MTIASSFTTPNGEEMIVLSRKDYEALIERIEDLEDSLAVVGFERKLAAGEEELIPAEYVNRMGEGESPIRVWRDFRGMAA
KDLAAAAGISTAYLSEIETGKKDGSVATLKAIADVLKLDLDDLYWRHEGRKVTDTA

Download         Length: 411 bp

>AT142849 NZ_CP060885:1352069-1352296 [Escherichia coli]
ATGGAAACTACTGTATTTTTAAGTAATCGCAGTCAGGCCGTCAGATTACCGAAAGCGGTCGCTCTGCCAGAAGACGTTAA
GAAAGTAGAAATTATTGCGATTGGTCGTACAAGAATCATCACTCCCGCCGGTGAGTCCTGGGACAGTTGGTTTGATGGCG
AAAATGTGAGTGCGGATTTTATGGATATCCGTGATCAACCCGCAATGCAGGAAAGGGAATCATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References