Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relE/YoeB-YefM
Location 1547268..1547773 Replicon chromosome
Accession NZ_CP045854
Organism Agrobacterium sp. MA01

Toxin (Protein)


Gene name yoeB Uniprot ID A0A0N1ATC5
Locus tag GH983_RS07565 Protein ID WP_054150123.1
Coordinates 1547268..1547522 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A0N1L550
Locus tag GH983_RS07570 Protein ID WP_054150137.1
Coordinates 1547519..1547773 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GH983_RS07540 1543005..1544429 - 1425 WP_153762060.1 3-mercaptopyruvate sulfurtransferase -
GH983_RS07545 1544456..1545187 - 732 WP_153762061.1 alanyl-tRNA editing protein -
GH983_RS07550 1545208..1546245 - 1038 WP_054150120.1 cysteine synthase A -
GH983_RS07555 1546455..1546901 - 447 WP_153762062.1 type II toxin-antitoxin system VapC family toxin -
GH983_RS07560 1546894..1547148 - 255 WP_054150122.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
GH983_RS07565 1547268..1547522 - 255 WP_054150123.1 Txe/YoeB family addiction module toxin Toxin
GH983_RS07570 1547519..1547773 - 255 WP_054150137.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GH983_RS07575 1547864..1549309 - 1446 WP_069043822.1 DNA photolyase family protein -
GH983_RS07580 1549418..1549642 - 225 WP_054150124.1 hypothetical protein -
GH983_RS07590 1550052..1550333 + 282 WP_153762064.1 hypothetical protein -
GH983_RS07595 1550489..1550713 + 225 WP_150127398.1 hypothetical protein -
GH983_RS07605 1551128..1551796 + 669 WP_194842833.1 protein-L-isoaspartate O-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10126.57 Da        Isoelectric Point: 9.9074

>T142847 WP_054150123.1 NZ_CP045854:c1547522-1547268 [Agrobacterium sp. MA01]
VKLIFHARAWEDYLYWQSTDPKMLARVNQLIKDSSRSPFHGIGKPEPLRGELRGWWSRRIDQEHRLVYRPTEDGLLIAQC
RHHY

Download         Length: 255 bp

>T142847 NZ_CP060885:1052996-1053331 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9492.62 Da        Isoelectric Point: 4.7037

>AT142847 WP_054150137.1 NZ_CP045854:c1547773-1547519 [Agrobacterium sp. MA01]
MRTTSYSDLRKNLASLLDSVTEDRTPVLITRDRGKPAAVLMSVEDFASYEETQHLLKSPRNAERLLEAVRDLDEGKGEAR
ELSE

Download         Length: 255 bp

>AT142847 NZ_CP060885:1052748-1052996 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0N1ATC5

Antitoxin

Source ID Structure
AlphaFold DB A0A0N1L550

References