Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 982896..983677 Replicon chromosome
Accession NZ_CP045854
Organism Agrobacterium sp. MA01

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag GH983_RS04700 Protein ID WP_153761766.1
Coordinates 982896..983414 (-) Length 173 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag GH983_RS04705 Protein ID WP_210251774.1
Coordinates 983417..983677 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GH983_RS04680 977962..979173 - 1212 WP_194842826.1 ROK family transcriptional regulator -
GH983_RS04685 979413..980453 + 1041 WP_054151103.1 D-xylose ABC transporter substrate-binding protein -
GH983_RS04690 980699..982012 + 1314 WP_054151102.1 sugar ABC transporter permease -
GH983_RS04695 982027..982812 + 786 WP_054151101.1 sugar ABC transporter ATP-binding protein -
GH983_RS04700 982896..983414 - 519 WP_153761766.1 GNAT family N-acetyltransferase Toxin
GH983_RS04705 983417..983677 - 261 WP_210251774.1 DUF1778 domain-containing protein Antitoxin
GH983_RS04710 983904..984410 + 507 WP_153761768.1 DUF305 domain-containing protein -
GH983_RS04715 984448..985857 - 1410 WP_153763555.1 methyl-accepting chemotaxis protein -
GH983_RS04720 986595..986978 - 384 WP_054151096.1 MAPEG family protein -
GH983_RS04725 987179..987838 + 660 WP_054151095.1 hemolysin III family protein -
GH983_RS04730 987994..988473 - 480 WP_153761769.1 ABZJ_00895 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-143)

Antitoxin

Vibrio phage ICP1, Orf50

(2-79)


Sequences

Toxin        


Download         Length: 173 a.a.        Molecular weight: 18172.88 Da        Isoelectric Point: 7.8308

>T142846 WP_153761766.1 NZ_CP045854:c983414-982896 [Agrobacterium sp. MA01]
MALSAPEPLHDGHDLSGFSCGKPALDIWLKTRARANQENGFTVVIVVHDAGRVVGYCGLSPTAALAASLPRSIRTGQPPD
PVPCLLLGQLAVDQSYAGHGIGTGLIKHALTRCVQGAALIGGRALIANAIDEEARLFWTRHGFLPSKDDPFRLLRPISHI
AAALEAAEKHHG

Download         Length: 519 bp

>T142846 NZ_CP060885:911405-911812 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9694.19 Da        Isoelectric Point: 4.4189

>AT142846 WP_210251774.1 NZ_CP045854:c983677-983417 [Agrobacterium sp. MA01]
MRLPEADVAMIDRAAALKGRSRTDFVRDAAVRAAEEALMEQQLIRMTEEGFADFMALMVAPAEVVPELVEVMRRPAPWEA
DYRAKD

Download         Length: 261 bp

>AT142846 NZ_CP060885:911158-911424 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References