Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | spoIISABC/SpoIISA-SpoIISB |
Location | 1348032..1348948 | Replicon | chromosome |
Accession | NZ_CP045812 | ||
Organism | Bacillus subtilis strain P8_B3 |
Toxin (Protein)
Gene name | spoIISA | Uniprot ID | O34853 |
Locus tag | GII89_RS07075 | Protein ID | WP_003244695.1 |
Coordinates | 1348202..1348948 (-) | Length | 249 a.a. |
Antitoxin (Protein)
Gene name | spoIISB | Uniprot ID | G4EXD8 |
Locus tag | GII89_RS07070 | Protein ID | WP_003232646.1 |
Coordinates | 1348032..1348202 (-) | Length | 57 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GII89_RS07035 | 1344895..1345224 | + | 330 | WP_003232660.1 | phage-like element PBSX protein XkdW | - |
GII89_RS07040 | 1345221..1345385 | + | 165 | WP_003232658.1 | XkdX family protein | - |
GII89_RS07045 | 1345429..1346268 | + | 840 | WP_003245597.1 | phage-like element PBSX protein XepA | - |
GII89_RS07050 | 1346321..1346590 | + | 270 | WP_003232655.1 | hemolysin XhlA family protein | - |
GII89_RS07055 | 1346603..1346866 | + | 264 | WP_003232653.1 | phage holin | - |
GII89_RS07060 | 1346879..1347772 | + | 894 | WP_003245230.1 | N-acetylmuramoyl-L-alanine amidase | - |
GII89_RS07065 | 1347809..1347946 | - | 138 | WP_003232648.1 | three component toxin-antitoxin-antitoxin system antitoxin SpoIISC | - |
GII89_RS07070 | 1348032..1348202 | - | 171 | WP_003232646.1 | three component toxin-antitoxin-antitoxin system antitoxin SpoIISB | Antitoxin |
GII89_RS07075 | 1348202..1348948 | - | 747 | WP_003244695.1 | toxin-antitoxin-antitoxin system toxin SpoIISA | Toxin |
GII89_RS07080 | 1349058..1350059 | - | 1002 | WP_003232642.1 | inorganic phosphate transporter | - |
GII89_RS07085 | 1350072..1350689 | - | 618 | WP_003218470.1 | DUF47 domain-containing protein | - |
GII89_RS07090 | 1350965..1352281 | - | 1317 | WP_003244819.1 | serine/threonine exchanger | - |
GII89_RS07095 | 1352670..1353620 | + | 951 | WP_003245086.1 | ring-cleaving dioxygenase | - |
GII89_RS07100 | 1353721..1353867 | + | 147 | WP_003244977.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 249 a.a. Molecular weight: 29061.50 Da Isoelectric Point: 4.6191
>T142630 WP_003244695.1 NZ_CP045812:c1348948-1348202 [Bacillus subtilis]
MVLFFQIMVWCIVAGLGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMVYWTYEPTSLFTHWERYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLNRLKTYQYLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNLTASL
CHYSTQADKDRLTEHMDDPADVQTRLDRKDVYYDQYGKVVLIPFTIETQNYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG
MVLFFQIMVWCIVAGLGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMVYWTYEPTSLFTHWERYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLNRLKTYQYLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNLTASL
CHYSTQADKDRLTEHMDDPADVQTRLDRKDVYYDQYGKVVLIPFTIETQNYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG
Download Length: 747 bp
>T142630 NZ_CP060796:c2509507-2509406 [Enterococcus faecalis]
TTGTCAATCGAAGCGGCATTGGAATTGATGATTAGTTTTGCAGCGTTTGTTGCGTTACTGATTTTCGGTATCCTTGAAGC
AACGAAAAACGATAAAAAATAA
TTGTCAATCGAAGCGGCATTGGAATTGATGATTAGTTTTGCAGCGTTTGTTGCGTTACTGATTTTCGGTATCCTTGAAGC
AACGAAAAACGATAAAAAATAA
Antitoxin
Download Length: 57 a.a. Molecular weight: 6654.72 Da Isoelectric Point: 11.0203
>AT142630 WP_003232646.1 NZ_CP045812:c1348202-1348032 [Bacillus subtilis]
MERAFQNRCEPRAAKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA
MERAFQNRCEPRAAKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA
Download Length: 171 bp
>AT142630 NZ_CP060796:2509283-2509461 [Enterococcus faecalis]
AAAAGAGAGGTATGCGGGTACATACCTCTCCTTTATACCAGCGCCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTT
TTTATTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCG
AAAATCAGTAACGCAACAA
AAAAGAGAGGTATGCGGGTACATACCTCTCCTTTATACCAGCGCCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTT
TTTATTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCG
AAAATCAGTAACGCAACAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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