Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 2727837..2728485 Replicon chromosome
Accession NZ_CP045809
Organism Gordonia pseudamarae strain CON9

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GII31_RS12065 Protein ID WP_213243356.1
Coordinates 2728066..2728485 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GII31_RS12060 Protein ID WP_213243354.1
Coordinates 2727837..2728064 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GII31_RS12040 (GII31_11975) 2723746..2724897 + 1152 WP_213243348.1 restriction endonuclease subunit S -
GII31_RS12045 (GII31_11980) 2724894..2725820 + 927 WP_213243350.1 restriction endonuclease -
GII31_RS12050 (GII31_11985) 2726034..2727272 - 1239 WP_213243352.1 HipA domain-containing protein -
GII31_RS12055 (GII31_11990) 2727269..2727574 - 306 WP_246221839.1 helix-turn-helix transcriptional regulator -
GII31_RS12060 (GII31_11995) 2727837..2728064 + 228 WP_213243354.1 ribbon-helix-helix protein, CopG family Antitoxin
GII31_RS12065 (GII31_12000) 2728066..2728485 + 420 WP_213243356.1 PIN domain nuclease Toxin
GII31_RS12070 (GII31_12005) 2728489..2731824 + 3336 WP_213243358.1 DEAD/DEAH box helicase family protein -
GII31_RS12075 (GII31_12010) 2731852..2732886 - 1035 WP_213243360.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(21-125)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-34)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15654.83 Da        Isoelectric Point: 5.2427

>T142621 WP_213243356.1 NZ_CP045809:2728066-2728485 [Gordonia pseudamarae]
MGDSGRWLIDKSAYARLRLSPDELTWVDRIQRGLVYVATPTLLEIGYSVRSGDEWERFQKHPPVSEMPTALFSERVDSRA
LEVQGLLARRGHHRAAKVPDLLIAAIAELSDLTVLHADKDFELIADITGQPMERLTGDF

Download         Length: 420 bp

>T142621 NZ_CP060789:c2905538-2905143 [Tessaracoccus defluvii]
GTGAGCGCCGGTCTGCTGGACACCAGCGTGTGGATCGCTGGGGAAGTGGGTCGGCTACTCGACACCGCCGCGCTTCCCGA
TGAGGCGTACGTCTGCGTCGTGACGCTCGCCGAGCTTCAGGCGGGCGTGTTGGCGGCGCCCGACACGCGGACGCGCGTGG
CCAGGCTGGCCACCGTCGAGAGACTCGCCGGCCTGGAGCCGCTGGCGGTAGACGGGGCGGTGGCCAGGCAGTGGGCGTCG
CTGCGGGTGCAGCTGCACGAGGCCGGTCGATCAATGGGGATCAATGATCTGTGGATCGCGGCCGTGGCGCTGGCCAACGG
ACTGCCGGTGGTCACTCAGGACTCGGGGTTCGACGTGCTCGGTGAGCTGGGCGCTCTCGAGGTGATCCGCGTGTAG

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8647.71 Da        Isoelectric Point: 5.6195

>AT142621 WP_213243354.1 NZ_CP045809:2727837-2728064 [Gordonia pseudamarae]
MTDILIRNVDDDDLRHIDALAAELGLSRTELLRRETKELARRHARSQVTVDDVRRSVDLARGALDEDLMRQAWGH

Download         Length: 228 bp

>AT142621 NZ_CP060789:c2905795-2905535 [Tessaracoccus defluvii]
ATGTCGACCGTCGCCTCCCGGGACCTCCGCAACCACACCCGCTCAGTCCTGGACCGCGTCGCTGCTGGGGACGTCGTCAC
CGTGACGGTGAATGGGGAGCCGGTTGCCGAGATCCGGAGCCCCACGAGGCGCAGGCCGGTCGCAATGAAGCGCTCCGACC
TGATCGACCTGGTGCACGCCCAGCGGGTAGACGTCACCCTTGAGGCGGACCTCGGGTGGATCTCCGCGGGTTCCACGGAA
GACCTCGGGCCCATCAGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References