Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 2041068..2041583 Replicon chromosome
Accession NZ_CP045809
Organism Gordonia pseudamarae strain CON9

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag GII31_RS09000 Protein ID WP_213248791.1
Coordinates 2041329..2041583 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GII31_RS08995 Protein ID WP_213248789.1
Coordinates 2041068..2041328 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GII31_RS08970 (GII31_08910) 2036383..2037009 + 627 WP_213248721.1 DUF177 domain-containing protein -
GII31_RS08975 (GII31_08915) 2037069..2037812 + 744 WP_246222178.1 ribonuclease III -
GII31_RS08980 (GII31_08920) 2037805..2038722 + 918 WP_260840389.1 bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase -
GII31_RS08985 (GII31_08925) 2038751..2040001 + 1251 WP_213248785.1 VWA domain-containing protein -
GII31_RS08990 (GII31_08930) 2040026..2040946 - 921 WP_213248787.1 alpha/beta hydrolase -
GII31_RS08995 (GII31_08935) 2041068..2041328 + 261 WP_213248789.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GII31_RS09000 (GII31_08940) 2041329..2041583 + 255 WP_213248791.1 Txe/YoeB family addiction module toxin Toxin
GII31_RS09005 (GII31_08945) 2041868..2042293 + 426 WP_213248793.1 OsmC family protein -
GII31_RS09010 (GII31_08950) 2042389..2042670 + 282 WP_213248795.1 acylphosphatase -
GII31_RS09015 (GII31_08955) 2042756..2046361 + 3606 WP_213248797.1 chromosome segregation protein SMC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-66)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9902.40 Da        Isoelectric Point: 7.8768

>T142620 WP_213248791.1 NZ_CP045809:2041329-2041583 [Gordonia pseudamarae]
MRLVWDLAAWEDYTHWQSVDRRVLKRINVLIDACLREPFEGIGKPERLKYGAAGACSRRITDEHRLVYLVDGSDLIILQA
RYHY

Download         Length: 255 bp

>T142620 NZ_CP060789:2205244-2205570 [Tessaracoccus defluvii]
ATGAGGCGAGCAGAGGTGTGGACCGTGGCGGGCGGGATCTCTGCCTCCAAACCTCGTCCGGCCATAATCGTCCAAGACGA
TGTCTTCGAACTCACAGATTCAATCACCGTCGCTCCCCTGACGACGACCCTGGTCGATGCGCCCCTCCTTCGCCTCCGGG
TCCCAGCGGGCGGTCTCACCGGCCTTGCTCAGGACAGCGACGTGATGGTGGACAAGCTGACGACTGTGCGACGCAGCAAT
GTGCAGGTCAGGATCGGGCGCCTCTCAAGGCAGCAGATGGTCGAGTTGGAGCGCCTCCTGATGACATTCCTTGGGATGGC
CCGATAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9788.82 Da        Isoelectric Point: 4.6926

>AT142620 WP_213248789.1 NZ_CP045809:2041068-2041328 [Gordonia pseudamarae]
MSISASEARKTLFPLIERVNEDRDAIEIVSRKGNAVLMSADEYAAWQETAYLFRSPANARRLLDAYERARGGRTEVHELD
RSDDTD

Download         Length: 261 bp

>AT142620 NZ_CP060789:2205041-2205247 [Tessaracoccus defluvii]
ATGGCCGTCAGCGATCGAGTGGGGCAACATCGCCACCGGATGCGAGCACGGGGCTACCGCCCGGTGCAGATCTGGGTGCC
CGACGTGCGCACCGAGCAGTTCGCGCGCGAGGCTGGTCACCAGGCGGCGCTCGTCGCGCAGAACGACCGTGAAGGAGATG
ACCAGGACTTCATCGAGGCCGTGACGGTGGGCTGGGACGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References