Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpIK/MazF(toxin)
Location 4603706..4604274 Replicon chromosome
Accession NZ_CP045806
Organism Gordonia pseudamarae strain BEN371

Toxin (Protein)


Gene name chpK Uniprot ID -
Locus tag GII33_RS20010 Protein ID WP_213245049.1
Coordinates 4603706..4604053 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name chpI Uniprot ID -
Locus tag GII33_RS20015 Protein ID WP_213245050.1
Coordinates 4604041..4604274 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GII33_RS19990 (GII33_19990) 4599227..4600024 - 798 WP_213250753.1 alpha/beta hydrolase -
GII33_RS19995 (GII33_19995) 4600024..4600770 - 747 WP_213245046.1 nitroreductase -
GII33_RS20000 (GII33_20000) 4601083..4602480 + 1398 WP_213245047.1 oxygenase MpaB family protein -
GII33_RS20005 (GII33_20005) 4602477..4603637 + 1161 WP_213245048.1 CaiB/BaiF CoA-transferase family protein -
GII33_RS20010 (GII33_20010) 4603706..4604053 - 348 WP_213245049.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
GII33_RS20015 (GII33_20015) 4604041..4604274 - 234 WP_213245050.1 hypothetical protein Antitoxin
GII33_RS20020 (GII33_20020) 4604376..4605506 - 1131 WP_213245051.1 acyl-CoA dehydrogenase family protein -
GII33_RS20025 (GII33_20025) 4605515..4606702 - 1188 WP_213245052.1 acyl-CoA dehydrogenase family protein -
GII33_RS20030 (GII33_20030) 4606825..4608900 + 2076 WP_246221966.1 NAD(P)/FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(5-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12401.30 Da        Isoelectric Point: 8.0236

>T142615 WP_213245049.1 NZ_CP045806:c4604053-4603706 [Gordonia pseudamarae]
VAVVERGDVWWVDFGEPLGSEPGYRRPALIVSSDRFNRSRMATVIVSAVTSNLRLAAAPGNVELAAGTAGLPKDCVVNVS
QTLVVDRARLTEPIGTLAFHIMRRVDDGLRLVFAV

Download         Length: 348 bp

>T142615 NZ_CP060783:c4536595-4536176 [Diaphorobacter aerolatus]
ATGATTCTGCTCGACACCAATGTGATGTTGGAGCCTCTCCGGCACGCTCCTGAGCCGCGGGTGATCGAGTGGATCGACGC
CCAGGCGATGGATACTTTGTTCCTTTCCGCCATCACGGTGGCCGAATTGCGGGCGGGTGTCGTCTTGCTGCCGGCTGGCA
AGCGGCGCGCATGCCTGCAAGAGAACTTGGAAAAGCGCGTGCTGCCGTTGTTTGCTGGCCGGGTACTGCCCTTTGACTTA
GCCTGCACCCAGGCCTATGCGGCGCTGATGGCCAAGGCACGCGCCGTGGGCACGGCCATCTCTTCGGCAGACGCCTACAT
CGCCGCCATCGCATCGGCCAATGGATTTGCCGTTGCAACGCGGGATACCAGTCTCTTCGAAGCAGCGGGCGCAGGCGTGA
TCAACCCATGGCAAGGGTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8551.42 Da        Isoelectric Point: 4.2264

>AT142615 WP_213245050.1 NZ_CP045806:c4604274-4604041 [Gordonia pseudamarae]
MKTAISIPDDVFREADSAANRLGWSRSQLYTRAVREFLERQEEDSVTAALNDIADGLNSDPVPAVGRSLIESGAWQW

Download         Length: 234 bp

>AT142615 NZ_CP060783:c4536846-4536592 [Diaphorobacter aerolatus]
ATGGCCATGCTGACAGTTCGAAATCTTCCCGAGGAAGTGCACCGTGCTCTACGCGTTCGCGCTGCCCAGCACGGCCAGAG
CATGGAGGCTGAAGTGCGCGAGATTTTGGAGTCAGCGATTAGTCCCAAAGGGCGCGTGAAGCTGGGTTCGCTCCTGGCTG
ACATGGGCCGCCAAGCCAAGCTGAGTGATGAAGAGTTTGCTGTGTTCGAGCAGGTGCGCGACGAAACGCCTGCGCGTCCG
GTGAGCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References