Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 2763459..2764107 Replicon chromosome
Accession NZ_CP045806
Organism Gordonia pseudamarae strain BEN371

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GII33_RS12180 Protein ID WP_213243356.1
Coordinates 2763688..2764107 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GII33_RS12175 Protein ID WP_213243354.1
Coordinates 2763459..2763686 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GII33_RS12155 (GII33_12145) 2759368..2760519 + 1152 WP_213243348.1 restriction endonuclease subunit S -
GII33_RS12160 (GII33_12150) 2760516..2761442 + 927 WP_213243350.1 restriction endonuclease -
GII33_RS12165 (GII33_12155) 2761656..2762894 - 1239 WP_213243352.1 HipA domain-containing protein -
GII33_RS12170 (GII33_12160) 2762891..2763196 - 306 WP_246221839.1 helix-turn-helix transcriptional regulator -
GII33_RS12175 (GII33_12165) 2763459..2763686 + 228 WP_213243354.1 ribbon-helix-helix protein, CopG family Antitoxin
GII33_RS12180 (GII33_12170) 2763688..2764107 + 420 WP_213243356.1 PIN domain nuclease Toxin
GII33_RS12185 (GII33_12175) 2764111..2767446 + 3336 WP_213243358.1 DEAD/DEAH box helicase family protein -
GII33_RS12190 (GII33_12180) 2767474..2768508 - 1035 WP_213243360.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(21-125)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-34)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15654.83 Da        Isoelectric Point: 5.2427

>T142613 WP_213243356.1 NZ_CP045806:2763688-2764107 [Gordonia pseudamarae]
MGDSGRWLIDKSAYARLRLSPDELTWVDRIQRGLVYVATPTLLEIGYSVRSGDEWERFQKHPPVSEMPTALFSERVDSRA
LEVQGLLARRGHHRAAKVPDLLIAAIAELSDLTVLHADKDFELIADITGQPMERLTGDF

Download         Length: 420 bp

>T142613 NZ_CP060780:c983981-983688 [Sphingomonas daechungensis]
TTGATCGAGGTCCGGCAGACCACTCGATTTGCGACATGGTTGGCAGGTCTGCGTGACGAACGCGCCCGGGCTCGCATCCT
GAAGAGGCTTGATCGGGCTGGGCAAGGAAATTTGGGAGACGTCGCTCCGGTTGGAGATGGAGTCTCGGAGATAAGAATTT
TCTACGGCCCGGGCTATCGCGTCTATTTTATCCAGCGAGGTTCGGAGCTGATCGTCTTGCTATGCGGCGGCGACAAGTCG
ACGCAGAGCGCGGACATCGAGGAAGCAAAGGCTTTGGCTAAGGAGGTTGATTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8647.71 Da        Isoelectric Point: 5.6195

>AT142613 WP_213243354.1 NZ_CP045806:2763459-2763686 [Gordonia pseudamarae]
MTDILIRNVDDDDLRHIDALAAELGLSRTELLRRETKELARRHARSQVTVDDVRRSVDLARGALDEDLMRQAWGH

Download         Length: 228 bp

>AT142613 NZ_CP060780:c983688-983392 [Sphingomonas daechungensis]
ATGGCCAAGATCGAAACCACGGCTTTCGACTCCGCCGACTATCTCAACACCGCCGAAACCATCGCAGCCTATCTCGATGC
CTATCTCGAGGATTCCACTCCCGAGGAGCTTCGCACTGCTCTTGCGACCGTCGCGCGTTCCCATGGCATTTCGGATTTGG
CTCGGCGCAGCGGCATCAGTCGTCCGGGAATCTACAAGGCGCTCGGCCAAGATGGGAACCCGTCGTTCGAGACGATCCGC
GCTATCCTGAGCGCGATGGGGTTGCGATTGACGGTGGAGCCTGCGGAGGTCGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References