Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 2081721..2082236 Replicon chromosome
Accession NZ_CP045806
Organism Gordonia pseudamarae strain BEN371

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag GII33_RS09155 Protein ID WP_213248791.1
Coordinates 2081982..2082236 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GII33_RS09150 Protein ID WP_213248789.1
Coordinates 2081721..2081981 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GII33_RS09125 (GII33_09115) 2077150..2077467 - 318 WP_213248775.1 helix-turn-helix domain-containing protein -
GII33_RS09130 (GII33_09120) 2077718..2079178 - 1461 WP_213248777.1 recombinase family protein -
GII33_RS09135 (GII33_09125) 2079217..2079375 + 159 Protein_1803 DNA-formamidopyrimidine glycosylase -
GII33_RS09140 (GII33_09130) 2079404..2080654 + 1251 WP_213248785.1 VWA domain-containing protein -
GII33_RS09145 (GII33_09135) 2080679..2081599 - 921 WP_213248787.1 alpha/beta hydrolase -
GII33_RS09150 (GII33_09140) 2081721..2081981 + 261 WP_213248789.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GII33_RS09155 (GII33_09145) 2081982..2082236 + 255 WP_213248791.1 Txe/YoeB family addiction module toxin Toxin
GII33_RS09160 (GII33_09150) 2082521..2082946 + 426 WP_213248793.1 OsmC family protein -
GII33_RS09165 (GII33_09155) 2083042..2083323 + 282 WP_213248795.1 acylphosphatase -
GII33_RS09170 (GII33_09160) 2083409..2087014 + 3606 WP_213248797.1 chromosome segregation protein SMC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-66)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9902.40 Da        Isoelectric Point: 7.8768

>T142612 WP_213248791.1 NZ_CP045806:2081982-2082236 [Gordonia pseudamarae]
MRLVWDLAAWEDYTHWQSVDRRVLKRINVLIDACLREPFEGIGKPERLKYGAAGACSRRITDEHRLVYLVDGSDLIILQA
RYHY

Download         Length: 255 bp

>T142612 NZ_CP060780:c983688-983392 [Sphingomonas daechungensis]
ATGGCCAAGATCGAAACCACGGCTTTCGACTCCGCCGACTATCTCAACACCGCCGAAACCATCGCAGCCTATCTCGATGC
CTATCTCGAGGATTCCACTCCCGAGGAGCTTCGCACTGCTCTTGCGACCGTCGCGCGTTCCCATGGCATTTCGGATTTGG
CTCGGCGCAGCGGCATCAGTCGTCCGGGAATCTACAAGGCGCTCGGCCAAGATGGGAACCCGTCGTTCGAGACGATCCGC
GCTATCCTGAGCGCGATGGGGTTGCGATTGACGGTGGAGCCTGCGGAGGTCGGATAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9788.82 Da        Isoelectric Point: 4.6926

>AT142612 WP_213248789.1 NZ_CP045806:2081721-2081981 [Gordonia pseudamarae]
MSISASEARKTLFPLIERVNEDRDAIEIVSRKGNAVLMSADEYAAWQETAYLFRSPANARRLLDAYERARGGRTEVHELD
RSDDTD

Download         Length: 261 bp

>AT142612 NZ_CP060780:c983981-983688 [Sphingomonas daechungensis]
TTGATCGAGGTCCGGCAGACCACTCGATTTGCGACATGGTTGGCAGGTCTGCGTGACGAACGCGCCCGGGCTCGCATCCT
GAAGAGGCTTGATCGGGCTGGGCAAGGAAATTTGGGAGACGTCGCTCCGGTTGGAGATGGAGTCTCGGAGATAAGAATTT
TCTACGGCCCGGGCTATCGCGTCTATTTTATCCAGCGAGGTTCGGAGCTGATCGTCTTGCTATGCGGCGGCGACAAGTCG
ACGCAGAGCGCGGACATCGAGGAAGCAAAGGCTTTGGCTAAGGAGGTTGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References