Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PHD(antitoxin)
Location 24512..25188 Replicon chromosome
Accession NZ_CP045806
Organism Gordonia pseudamarae strain BEN371

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GII33_RS00110 Protein ID WP_213245675.1
Coordinates 24512..24922 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GII33_RS00115 Protein ID WP_213245677.1
Coordinates 24925..25188 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GII33_RS00095 (GII33_00100) 20429..21679 + 1251 WP_246222020.1 hypothetical protein -
GII33_RS00100 (GII33_00105) 21733..23025 + 1293 WP_246222373.1 lipase family protein -
GII33_RS00105 (GII33_00110) 23234..24427 + 1194 WP_213245673.1 MFS transporter -
GII33_RS00110 (GII33_00115) 24512..24922 - 411 WP_213245675.1 type II toxin-antitoxin system VapC family toxin Toxin
GII33_RS00115 (GII33_00120) 24925..25188 - 264 WP_213245677.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GII33_RS00120 (GII33_00125) 25394..25696 - 303 WP_246222021.1 excisionase family DNA-binding protein -
GII33_RS00125 (GII33_00130) 25981..26709 + 729 WP_213245681.1 hypothetical protein -
GII33_RS00130 (GII33_00135) 26738..27310 - 573 WP_213245682.1 XRE family transcriptional regulator -
GII33_RS00135 (GII33_00140) 27430..28869 + 1440 WP_246222022.1 MFS transporter -
GII33_RS00140 (GII33_00145) 29189..29689 + 501 WP_213245685.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-42)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14615.78 Da        Isoelectric Point: 4.3652

>T142611 WP_213245675.1 NZ_CP045806:c24922-24512 [Gordonia pseudamarae]
MAYYIDTSALVKFVVAEPESSTLHRWLIEEDPVLVSCDLARTELIRAVRLAGGDMVRARLVLSSITLTTLSGATFTAAAL
LEPPLLRSLDAVHIAAALELGDDLDGLVTYDTRMADAATHQGIPMLAPGPDDERAR

Download         Length: 411 bp

>T142611 NZ_CP060753:22771-22929 [Escherichia coli]
ATGAAACTACCACGAAGTTCCCTTGTCTGGTGTGTGTTGATCGTGTGTCTCACACTGTTGATATTCACTTATCTGACACG
AAAATCGCTGTGCGAGATTCGTTACAGAGACGGACACAGGGAGGTGGCGGCTTTCATGGCTTACGAATCCGGTAAGTAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9087.35 Da        Isoelectric Point: 7.2049

>AT142611 WP_213245677.1 NZ_CP045806:c25188-24925 [Gordonia pseudamarae]
MTEVGIRALKQNASAVVAEAASGETVVITDHGRPVAQLSPISASPLERMVAAGRARPPKSALRDLPEPSPGPELSAALAQ
LRETEHR

Download         Length: 264 bp

>AT142611 NZ_CP060753:22660-22725 [Escherichia coli]
AGAAGATAGCCCCGTAGTAAGTTAATTTTCATTAACCACCACGAGGCATCCCTATGTCTAGTCCAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References