Detailed information of TA system TA142605

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/LOTUS_5_Limkain_b1-Phd
• Location: 1107971..1108635
• Replicon: chromosome
• Accession: NZ_CP045802
• Organism: Paenibacillus sp. B01

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: GE073_RS04835
• Protein ID: WP_101808601.1
• Coordinates: 1108210..1108635 (+)
• Length: 142 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: GE073_RS04830
• Protein ID: WP_101808600.1
• Coordinates: 1107971..1108213 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GE073_RS04810	1103081..1104304	+	1224	WP_153784660.1	YbfB/YjiJ family MFS transporter	-
GE073_RS04815	1104345..1105043	-	699	WP_153782886.1	hypothetical protein	-
GE073_RS04820	1105195..1106550	+	1356	WP_153782887.1	PQQ-binding-like beta-propeller repeat protein	-
GE073_RS04825	1106634..1107782	-	1149	WP_153782888.1	copper amine oxidase N-terminal domain-containing protein	-
GE073_RS04830	1107971..1108213	+	243	WP_101808600.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
GE073_RS04835	1108210..1108635	+	426	WP_101808601.1	type II toxin-antitoxin system VapC family toxin	Toxin
GE073_RS04840	1108747..1109910	+	1164	WP_153784661.1	multidrug effflux MFS transporter	-
GE073_RS04845	1110425..1111747	+	1323	WP_180968452.1	MFS transporter	-
GE073_RS04850	1111803..1112054	-	252	WP_127464482.1	hypothetical protein	-
GE073_RS04855	1112051..1113067	-	1017	WP_153782890.1	nucleotide-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-123)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-56)

Sequences

Toxin

Protein

• Length: 142 a.a.
• Molecular weight: 15927.17 Da
• Isoelectric Point: 5.2130

>T142605 WP_101808601.1 NZ_CP045802:1108210-1108635 [Paenibacillus sp. B01]
MNYLLDTNVISELVKKEPDSGVLRWIDERDESTLFLSVITFGELQKGISKLSDKNRAERLQVWIDQDLSSRFDGRVLPLD
LDTLLAWGSIQGQAERNGTPLPVMDSLIAATAIAHHLTVVTRNVHDLERCKASVFNPWINK

Nucleotide

• Length: 426 bp

>T142605 NZ_CP060748:c3968080-3967907 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9202.56 Da
• Isoelectric Point: 4.7265

>AT142605 WP_101808600.1 NZ_CP045802:1107971-1108213 [Paenibacillus sp. B01]
MMQWQLQDAKNQLSSVVKKAADEGPQMITVRGMPAAVVLSMEEYQRLTKPKTRLTDFFKDSPLYDLDLDRSQDIAREVDL

Nucleotide

• Length: 243 bp

>AT142605 NZ_CP060748:c3968404-3968108 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGATT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTCAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG