Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4000842..4001076 | Replicon | chromosome |
| Accession | NZ_CP045784 | ||
| Organism | Shigella dysenteriae strain CFSAN029786 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4000972..4001075 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4000842..4001076 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GH770_RS20385 | 3996061..3996723 | - | 663 | WP_000944260.1 | exodeoxyribonuclease X | - |
| GH770_RS20390 | 3996747..3997403 | - | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| GH770_RS20395 | 3997505..3997735 | - | 231 | WP_000916761.1 | DNA polymerase III subunit theta | - |
| GH770_RS20400 | 3997874..3998248 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| GH770_RS20410 | 3999639..4000460 | + | 822 | WP_046891729.1 | copper homeostasis membrane protein CopD | - |
| GH770_RS20415 | 4000473..4000814 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 4000842..4001076 | - | 235 | - | - | Antitoxin |
| - | 4000972..4001075 | + | 104 | - | - | Toxin |
| GH770_RS20420 | 4001207..4001734 | - | 528 | Protein_4011 | tyrosine-type recombinase/integrase | - |
| GH770_RS20425 | 4001800..4002956 | + | 1157 | Protein_4012 | IS3 family transposase | - |
| GH770_RS20430 | 4002999..4003440 | - | 442 | Protein_4013 | integrase | - |
| GH770_RS20435 | 4003512..4004679 | + | 1168 | WP_129592854.1 | IS3 family transposase | - |
| GH770_RS20440 | 4004688..4005037 | - | 350 | Protein_4015 | transposase | - |
| GH770_RS20445 | 4005143..4005523 | + | 381 | WP_001333468.1 | transposase | - |
| GH770_RS20450 | 4005520..4005867 | + | 348 | WP_000612610.1 | IS66 family insertion sequence element accessory protein TnpB | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 3991314..4052808 | 61494 | |
| - | inside | IScluster/Tn | - | ipaH9.8 | 3998305..4023706 | 25401 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T142580 NZ_CP045784:4000972-4001075 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCTCTGGACCGAATAC
AGGAATTGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCTCTGGACCGAATAC
AGGAATTGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT142580 NZ_CP045784:c4001076-4000842 [Shigella dysenteriae]
TAAAAAAAGACCGAATACAATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACAATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
