Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1059051..1059195 Replicon chromosome
Accession NZ_CP045783
Organism Klebsiella variicola strain LEMB11

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1059057..1059159 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1059051..1059195 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFC07_RS05100 1054574..1056007 + 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GFC07_RS05105 1056123..1056362 + 240 WP_002911393.1 YebV family protein -
GFC07_RS05110 1056460..1056651 + 192 WP_002911395.1 YebW family protein -
GFC07_RS05115 1056648..1057301 - 654 WP_008804273.1 protein-serine/threonine phosphatase -
GFC07_RS05120 1057457..1058425 + 969 WP_162493241.1 VirK/YbjX family protein -
GFC07_RS05125 1058529..1058672 + 144 WP_046621074.1 Ecr family regulatory small membrane protein -
- 1059051..1059195 + 145 - - Antitoxin
- 1059057..1059159 - 103 - - Toxin
GFC07_RS05130 1059317..1059655 - 339 WP_008804271.1 YebY family protein -
GFC07_RS05135 1059672..1060541 - 870 WP_100780970.1 copper homeostasis membrane protein CopD -
GFC07_RS05140 1060545..1060919 - 375 WP_038421459.1 CopC domain-containing protein YobA -
GFC07_RS05145 1061033..1061263 + 231 WP_100780971.1 DNA polymerase III subunit theta -
GFC07_RS05150 1061342..1062001 + 660 WP_008804267.1 exodeoxyribonuclease X -
GFC07_RS05155 1062005..1064065 - 2061 WP_012541258.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T142552 NZ_CP045783:c1059159-1059057 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT142552 NZ_CP045783:1059051-1059195 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References