Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1304211..1304356 | Replicon | chromosome |
| Accession | NZ_CP045782 | ||
| Organism | Klebsiella pneumoniae strain LEMB18 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1304218..1304320 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1304211..1304356 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GFB99_RS06440 | 1299743..1301176 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| GFB99_RS06445 | 1301292..1301531 | + | 240 | WP_002911393.1 | YebV family protein | - |
| GFB99_RS06450 | 1301629..1301820 | + | 192 | WP_002911395.1 | YebW family protein | - |
| GFB99_RS06455 | 1301817..1302470 | - | 654 | WP_023280291.1 | protein-serine/threonine phosphatase | - |
| GFB99_RS06460 | 1302627..1303595 | + | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| GFB99_RS06465 | 1303700..1303843 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 1304211..1304356 | + | 146 | - | - | Antitoxin |
| - | 1304218..1304320 | - | 103 | - | - | Toxin |
| GFB99_RS06470 | 1304479..1304817 | - | 339 | WP_002911404.1 | YebY family protein | - |
| GFB99_RS06475 | 1304834..1305703 | - | 870 | WP_023285313.1 | copper homeostasis membrane protein CopD | - |
| GFB99_RS06480 | 1305707..1306081 | - | 375 | WP_023285314.1 | CopC domain-containing protein YobA | - |
| GFB99_RS06485 | 1306194..1306424 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| GFB99_RS06490 | 1306503..1307162 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| GFB99_RS06495 | 1307166..1309226 | - | 2061 | WP_047694778.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T142533 NZ_CP045782:c1304320-1304218 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT142533 NZ_CP045782:1304211-1304356 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT