Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1304211..1304356 Replicon chromosome
Accession NZ_CP045782
Organism Klebsiella pneumoniae strain LEMB18

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1304218..1304320 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1304211..1304356 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFB99_RS06440 1299743..1301176 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GFB99_RS06445 1301292..1301531 + 240 WP_002911393.1 YebV family protein -
GFB99_RS06450 1301629..1301820 + 192 WP_002911395.1 YebW family protein -
GFB99_RS06455 1301817..1302470 - 654 WP_023280291.1 protein-serine/threonine phosphatase -
GFB99_RS06460 1302627..1303595 + 969 WP_004151446.1 VirK/YbjX family protein -
GFB99_RS06465 1303700..1303843 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1304211..1304356 + 146 - - Antitoxin
- 1304218..1304320 - 103 - - Toxin
GFB99_RS06470 1304479..1304817 - 339 WP_002911404.1 YebY family protein -
GFB99_RS06475 1304834..1305703 - 870 WP_023285313.1 copper homeostasis membrane protein CopD -
GFB99_RS06480 1305707..1306081 - 375 WP_023285314.1 CopC domain-containing protein YobA -
GFB99_RS06485 1306194..1306424 + 231 WP_002911406.1 DNA polymerase III subunit theta -
GFB99_RS06490 1306503..1307162 + 660 WP_002911407.1 exodeoxyribonuclease X -
GFB99_RS06495 1307166..1309226 - 2061 WP_047694778.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T142533 NZ_CP045782:c1304320-1304218 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT142533 NZ_CP045782:1304211-1304356 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References