Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/RelE-RHH |
Location | 56134..56681 | Replicon | plasmid pCFSAN000189 |
Accession | NZ_CP045752 | ||
Organism | Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000189 |
Toxin (Protein)
Gene name | parE | Uniprot ID | A0A4D6NZF1 |
Locus tag | GH766_RS00320 | Protein ID | WP_000970006.1 |
Coordinates | 56400..56681 (+) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | A0A4D6P197 |
Locus tag | GH766_RS00315 | Protein ID | WP_000084547.1 |
Coordinates | 56134..56403 (+) | Length | 90 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GH766_RS00285 | 51575..52141 | + | 567 | WP_000493830.1 | DUF2726 domain-containing protein | - |
GH766_RS00290 | 52138..52869 | + | 732 | WP_020833545.1 | type-F conjugative transfer system pilin acetylase TraX | - |
GH766_RS00295 | 53109..53579 | + | 471 | Protein_58 | phospholipase D family protein | - |
GH766_RS00300 | 53723..53989 | + | 267 | WP_001576653.1 | replication regulatory protein RepA | - |
GH766_RS00305 | 54239..54316 | + | 78 | WP_001541552.1 | RepA leader peptide Tap | - |
GH766_RS00310 | 54297..55178 | + | 882 | WP_023193063.1 | incFII family plasmid replication initiator RepA | - |
GH766_RS00315 | 56134..56403 | + | 270 | WP_000084547.1 | hypothetical protein | Antitoxin |
GH766_RS00320 | 56400..56681 | + | 282 | WP_000970006.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
GH766_RS00325 | 56833..57423 | - | 591 | WP_031607984.1 | plasmid pRiA4b ORF-3 family protein | - |
GH766_RS00330 | 58669..59178 | + | 510 | WP_131535394.1 | hypothetical protein | - |
GH766_RS00335 | 59487..60359 | + | 873 | WP_077915507.1 | helix-turn-helix transcriptional regulator | - |
GH766_RS00340 | 60556..61257 | + | 702 | WP_023251326.1 | transcriptional activator SprB | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..81815 | 81815 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 12066.38 Da Isoelectric Point: 12.7685
>T142469 WP_000970006.1 NZ_CP045752:56400-56681 [Salmonella enterica subsp. enterica serovar Bareilly str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKK
Download Length: 282 bp
>T142469 NZ_CP060704:5459989-5460294 [Chitinimonas koreensis]
ATGGCAGACACTGCAACCCGCGCCTGGGACCCGGCGGAACACCTCGATAGCGAAGAAGATATGGCGGCCTATCTCGAGGC
CGCCCTCGAAGACGGCGACCCGGCCCTGGTCACCGCCGCCTTGGGCGATATCGCCCGCGCCAAGGGCATGACCCGCATCG
CGCGCGAGGCCGGTCTGAGCCGCGAAAGCCTGTACAAGGCGCTTTCGCCCAACGGCAACCCGGAGCTGGCGACGATCCTG
AAGGTCGTCTCCGTGCTCGGCCTGCGGCTGCACGCTACCCCCGCACCGGCGAAGCTACCGGGATAG
ATGGCAGACACTGCAACCCGCGCCTGGGACCCGGCGGAACACCTCGATAGCGAAGAAGATATGGCGGCCTATCTCGAGGC
CGCCCTCGAAGACGGCGACCCGGCCCTGGTCACCGCCGCCTTGGGCGATATCGCCCGCGCCAAGGGCATGACCCGCATCG
CGCGCGAGGCCGGTCTGAGCCGCGAAAGCCTGTACAAGGCGCTTTCGCCCAACGGCAACCCGGAGCTGGCGACGATCCTG
AAGGTCGTCTCCGTGCTCGGCCTGCGGCTGCACGCTACCCCCGCACCGGCGAAGCTACCGGGATAG
Antitoxin
Download Length: 90 a.a. Molecular weight: 11553.68 Da Isoelectric Point: 12.7493
>AT142469 WP_000084547.1 NZ_CP045752:56134-56403 [Salmonella enterica subsp. enterica serovar Bareilly str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKK
Download Length: 270 bp
>AT142469 NZ_CP060704:5459688-5459978 [Chitinimonas koreensis]
ATGGTCGAGATACGTCAAACGGACGGTTACGCCCACTGGTTCGCAGGACTGCGGGATCGCACGGCACGCGCCCGGATCGA
CATCCGCATCCGCCGCCTGTCGCTCGACAACCCCGGCGACGTCAAACCCGTAGGCGGCGGCGTATCCGAGCTTCGCATCG
ACCGTGGGCCGGGCTATCGCATCTACTTCGTCCGGCGCGGCGACACGCTCGTCGTCCTGCTGGCCGGCGGCGGCAAGTCC
ACGCAGGAACAGGACATCCGGAACGCGCTCGAACTGGCCCGTTCGATCTGA
ATGGTCGAGATACGTCAAACGGACGGTTACGCCCACTGGTTCGCAGGACTGCGGGATCGCACGGCACGCGCCCGGATCGA
CATCCGCATCCGCCGCCTGTCGCTCGACAACCCCGGCGACGTCAAACCCGTAGGCGGCGGCGTATCCGAGCTTCGCATCG
ACCGTGGGCCGGGCTATCGCATCTACTTCGTCCGGCGCGGCGACACGCTCGTCGTCCTGCTGGCCGGCGGCGGCAAGTCC
ACGCAGGAACAGGACATCCGGAACGCGCTCGAACTGGCCCGTTCGATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A4D6NZF1 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A4D6P197 |