Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3003684..3003955 Replicon chromosome
Accession NZ_CP045741
Organism Escherichia coli strain DH5alpha

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3003814..3003917 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3003684..3003955 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GHR40_RS14280 3000239..3000901 - 663 WP_000944256.1 exodeoxyribonuclease X -
GHR40_RS14285 3000925..3001581 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
GHR40_RS14290 3001683..3001913 - 231 WP_000916763.1 DNA polymerase III subunit theta -
GHR40_RS14295 3002052..3002426 + 375 WP_000168747.1 CopC domain-containing protein YobA -
GHR40_RS14300 3002430..3003302 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
GHR40_RS14305 3003315..3003656 + 342 WP_000976476.1 YebY family protein -
- 3003684..3003955 - 272 - - Antitoxin
- 3003814..3003917 + 104 - - Toxin
GHR40_RS14310 3004052..3004708 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
GHR40_RS14315 3004709..3004900 - 192 WP_000457842.1 YebW family protein -
GHR40_RS14320 3005005..3005241 - 237 WP_001295499.1 DUF1480 family protein -
GHR40_RS14325 3005359..3006798 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T142448 NZ_CP045741:3003814-3003917 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT142448 NZ_CP045741:c3003955-3003684 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References