142395

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1035041..1035592 Replicon chromosome
Accession NZ_CP045725
Organism Raineyella sp. CBA3103

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag Rai3103_RS04780 Protein ID WP_153571621.1
Coordinates 1035041..1035355 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag Rai3103_RS04785 Protein ID WP_153573611.1
Coordinates 1035359..1035592 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Rai3103_RS04750 1030108..1030869 - 762 WP_153571616.1 precorrin-6A/cobalt-precorrin-6A reductase -
Rai3103_RS04755 1030866..1031401 - 536 Protein_926 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase -
Rai3103_RS04760 1031448..1031945 + 498 WP_153571617.1 low molecular weight phosphotyrosine protein phosphatase -
Rai3103_RS04765 1032055..1033368 + 1314 WP_153571618.1 YibE/F family protein -
Rai3103_RS04770 1033468..1033875 + 408 WP_153571619.1 VOC family protein -
Rai3103_RS04775 1034395..1035009 + 615 WP_153571620.1 cation diffusion facilitator family transporter -
Rai3103_RS04780 1035041..1035355 - 315 WP_153571621.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
Rai3103_RS04785 1035359..1035592 - 234 WP_153573611.1 ribbon-helix-helix protein, CopG family Antitoxin
Rai3103_RS16900 1036822..1037556 - 735 WP_194793274.1 hypothetical protein -
Rai3103_RS04795 1037646..1038209 + 564 WP_153571622.1 hypothetical protein -
Rai3103_RS04800 1038367..1039062 + 696 WP_153571623.1 NAD-dependent deacylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-94)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 10959.74 Da        Isoelectric Point: 4.7377

>T142395 WP_153571621.1 NZ_CP045725:c1035355-1035041 [Raineyella sp. CBA3103]
VREICLARLDKTRPVVVLTRDAARSAMTKVTVAPITSTIKGLSSEVPVGPENGLDHDGAISLDNVVTIPVALLGRTVGFL
TEVQEAGLARAVVLAYDLDLPLLD

Download         Length: 315 bp

>T142395 NZ_CP060674:4453094-4453405 [Salmonella enterica]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGAGGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8272.34 Da        Isoelectric Point: 4.5238

>AT142395 WP_153573611.1 NZ_CP045725:c1035592-1035359 [Raineyella sp. CBA3103]
MSVQIAIRLPDDMVAFLDQSVAAGNAPSRAALVARALEREMRRQAAERDAAILRAKGPADDLDDLVTWAASHSAVEE

Download         Length: 234 bp

>AT142395 NZ_CP060674:4453406-4453696 [Salmonella enterica]
ATGGATAAAGTGTTATTTGAGCGATTAACTCAAAGTATGTCTCAAATGAATGAAATCATTGAAGGGACCCGTGAGCCTTC
TCGTACCTTTCATATTGATGCAATGAAGATTAAAGAAATACGGCAGGCATCTGGGTTGTCGCAATCTAAGTTTGCAGAAC
TGATTTCGGTCAACGTGGATACGCTGCGCAACTGGGAGCAAGGAAGACGTTCACCGACAGGGCCAGCCAAAGCGTTACTT
CGCGCCATTGCCAACGACCCGAGAAACGTTATACAAGCATTGCGTTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References