Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 2078734..2080292 Replicon chromosome
Accession NZ_CP045720
Organism Pantoea eucalypti strain LMG 24197

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag EE896_RS09605 Protein ID WP_140915597.1
Coordinates 2078982..2080292 (+) Length 437 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag EE896_RS09600 Protein ID WP_003853619.1
Coordinates 2078734..2078982 (+) Length 83 a.a.

Genomic Context

EE896_RS09580EE896_RS09585EE896_RS09590EE896_RS09600EE896_RS09605EE896_RS09610EE896_RS09615EE896_RS09620EE896_RS09595EE896_RS09625
Location: 2073989..2076214 (2226 bp)
Type: Others
Protein ID: WP_039660224.1
Location: 2076211..2077272 (1062 bp)
Type: Others
Protein ID: WP_003853623.1
Location: 2077296..2078090 (795 bp)
Type: Others
Protein ID: WP_105099176.1
Location: 2078734..2078982 (249 bp)
Type: Antitoxin
Protein ID: WP_003853619.1
Location: 2078982..2080292 (1311 bp)
Type: Toxin
Protein ID: WP_140915597.1
Location: 2080394..2080600 (207 bp)
Type: Others
Protein ID: WP_003853616.1
Location: 2080902..2082284 (1383 bp)
Type: Others
Protein ID: WP_140915596.1
Location: 2082399..2084444 (2046 bp)
Type: Others
Protein ID: WP_140915595.1
Location: 2078120..2078557 (438 bp)
Type: Others
Protein ID: WP_140915598.1
Location: 2084784..2085119 (336 bp)
Type: Others
Protein ID: WP_105099181.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EE896_RS095802073989..2076214+2226WP_039660224.1iron ABC transporter permease-
EE896_RS095852076211..2077272+1062WP_003853623.1ABC transporter ATP-binding protein-
EE896_RS095902077296..2078090+795WP_105099176.1inositol monophosphatase-
EE896_RS095952078120..2078557-438WP_140915598.1GNAT family N-acetyltransferase-
EE896_RS096002078734..2078982+249WP_003853619.1type II toxin-antitoxin system antitoxin HipBAntitoxin
EE896_RS096052078982..2080292+1311WP_140915597.1type II toxin-antitoxin system HipA family toxinToxin
EE896_RS096102080394..2080600+207WP_003853616.1type II toxin-antitoxin system MqsA family antitoxin-
EE896_RS096152080902..2082284+1383WP_140915596.1M24 family metallopeptidase-
EE896_RS096202082399..2084444+2046WP_140915595.1FUSC family protein-
EE896_RS096252084784..2085119-336WP_105099181.1gamma-glutamylcyclotransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(148-401)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-64)


Sequences

Toxin        


Download         Length: 437 a.a.        Molecular weight: 49098.42 Da        Isoelectric Point: 6.6643

>T142384 WP_140915597.1 NZ_CP045720:2078982-2080292 [Pantoea eucalypti]
MQRLIAWMNGERVGVLTWQRNGTHAFQYDTGWLSNPLSRPLSLSMPLQVKAITSHAVINFFDNLLPDSPLIRERIAARYQ
TQSCEPFDLLQEVGRDTVGAIMLLPPDRPLPAVQARYEVLDEARLESVLSARYDIPLGMLHEEPDFRLSVAGAQEKTALL
LTQEGWSIPAGGTSASHIIKLPVGEIKQPTATLDMRESVENEYLCLTLARALGINVPQATIIRAGKMRALAVERFDRRWS
RDKTRLIRLPQEDFCQALGLTSSTQYESDGGPGIAEIMQILMGSRHAIEDRYRFMMFQVFQWLIGATDGHARNFSLFIER
GGSYRLTPFYDVISAYPVQSGSGMNTQTLTLAMGLGATQEKRTEIDKIYPRHFIATAKQVSFDRDSLQQIFDFFIKALPQ
AIVLVRDALPPDFPQHIADAIFSHALIMLERLRHGE

Download         Length: 1311 bp

>T142384 NZ_CP060674:c658362-658105 [Salmonella enterica]
ATGAATGCCTCCGGCGTCAGCGTCCGCCACATCAACAGCAAAACCCACATGACCACCTATTACTCACAAATCCCCAGCCT
GCATCTTAAGGGCGACTGGCTGGAAGAAGCGGGATTTAAGACCGGGCGCGGCGTCACCGTGAAGATTTCACAGGGGTGTA
TTGTGCTGATGGCGGACAGTAACGAGGAGCAGAAGCTGCGCGAGCAGCTTTATCAGGCTAAACAGGTGGTTAAGGGAATT
AAGGACGTGCTGGTTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9278.55 Da        Isoelectric Point: 6.2126

>AT142384 WP_003853619.1 NZ_CP045720:2078734-2078982 [Pantoea eucalypti]
MIYSPIQLANQLKFIRQRNGWTQSELAKKVGLKQATISHFENAPDSTSLATLFKLLQALEVSLAVQEKEAVTATHLHDED
EW

Download         Length: 249 bp

>AT142384 NZ_CP060674:658187-658519 [Salmonella enterica]
TCCGCCATCAGCACAATACACCCCTGTGAAATCTTCACGGTGACGCCGCGCCCGGTCTTAAATCCCGCTTCTTCCAGCCA
GTCGCCCTTAAGATGCAGGCTGGGGATTTGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTGATGTGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGCGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCC
GGGGCCGTATTTT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References