Detailed information of TA system TA142312

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafN(antitoxin)
• Location: 472475..473040
• Replicon: chromosome
• Accession: NZ_CP045700
• Organism: Vibrio sp. SM1977

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: GFB47_RS13850
• Protein ID: WP_153449014.1
• Coordinates: 472475..472762 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: GFB47_RS13855
• Protein ID: WP_178306520.1
• Coordinates: 472762..473040 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GFB47_RS13835	469211..470005	-	795	WP_153448626.1	ABC transporter ATP-binding protein	-
GFB47_RS13840	470004..470630	+	627	WP_153448627.1	multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1	-
GFB47_RS13845	470956..472176	+	1221	WP_153448628.1	trans-2-enoyl-CoA reductase family protein	-
GFB47_RS13850	472475..472762	-	288	WP_153449014.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
GFB47_RS13855	472762..473040	-	279	WP_178306520.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
GFB47_RS13860	473295..474950	+	1656	WP_153448629.1	ABC-ATPase domain-containing protein	-
GFB47_RS13865	475189..475689	+	501	WP_153448630.1	M48 family metallopeptidase	-
GFB47_RS13870	475694..475861	-	168	WP_153448631.1	hypothetical protein	-
GFB47_RS13875	475928..476074	+	147	WP_153448632.1	IS3 family transposase	-
GFB47_RS13880	476246..476620	-	375	WP_153448633.1	AzlD domain-containing protein	-
GFB47_RS13885	476632..477426	-	795	WP_153448634.1	AzlC family ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-73)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10974.75 Da
• Isoelectric Point: 5.8289

>T142312 WP_153449014.1 NZ_CP045700:c472762-472475 [Vibrio sp. SM1977]
MKVVWSPLALEKLGDAAEFIALDSPATAKKWVNEVFDKTNSLGTMPEMGRMVPEMPHTNYREILFGYYRIIYSVGVEFRV
LTIRNCRQILTENDF

Nucleotide

• Length: 288 bp

>T142312 NZ_CP060666:c2334693-2334590 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10372.81 Da
• Isoelectric Point: 4.8723

>AT142312 WP_178306520.1 NZ_CP045700:c473040-472762 [Vibrio sp. SM1977]
MSRIHFDQDIQPLSEFRAGVTSFIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEELRTAEAQFASGLGVSN
EEARDQVLGRIK

Nucleotide

• Length: 279 bp

>AT142312 NZ_CP060666:2334588-2334733 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG