Detailed information of TA system TA142311

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 135308..136068
• Replicon: chromosome
• Accession: NZ_CP045700
• Organism: Vibrio sp. SM1977

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: GFB47_RS12100
• Protein ID: WP_153448320.1
• Coordinates: 135565..136068 (+)
• Length: 168 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: GFB47_RS12095
• Protein ID: WP_153448319.1
• Coordinates: 135308..135574 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GFB47_RS12075	130671..131669	-	999	WP_153448315.1	1-phosphofructokinase	-
GFB47_RS12080	131679..132812	-	1134	WP_153448316.1	fused PTS fructose transporter subunit IIA/HPr protein	-
GFB47_RS12085	133216..134238	+	1023	WP_153448317.1	catabolite repressor/activator	-
GFB47_RS12090	134283..135179	+	897	WP_153448318.1	DMT family transporter	-
GFB47_RS12095	135308..135574	+	267	WP_153448319.1	DUF1778 domain-containing protein	Antitoxin
GFB47_RS12100	135565..136068	+	504	WP_153448320.1	GNAT family N-acetyltransferase	Toxin
GFB47_RS12105	136260..137591	+	1332	WP_153448321.1	DEAD/DEAH box helicase	-
GFB47_RS12110	137688..138605	+	918	WP_153448322.1	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase	-
GFB47_RS12115	138723..139682	-	960	WP_153448323.1	agmatinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (42-145)

Antitoxin

• Vibrio phage ICP1, Orf50 (8-83)

Sequences

Toxin

Protein

• Length: 168 a.a.
• Molecular weight: 18209.00 Da
• Isoelectric Point: 6.9571

>T142311 WP_153448320.1 NZ_CP045700:135565-136068 [Vibrio sp. SM1977]
MAITSPQLLMAEHLLSSFSCGIDDLDDWLIKKAIKNQNRNNTRVYVVVDQTTDQVVGYYAIAMGSILRVSAIGSLRRNSP
DPIPMVVLARLGVHRDFQHLGIGAGLLKDCVLRSVQAMNVIGGAGILVHAIDESAKSFYSKFGFSESSFDPLLLMARTCD
IEASHSN

Nucleotide

• Length: 504 bp

>T142311 NZ_CP060666:c2085225-2085070 [Salmonella enterica]
ATGAAGCAGCAAAAGGCGATGTTAATCGCCCTGATCGTCATCTGTTTAACCGTCATAGTGACGGCACTGGTAACGAGGAA
AGACCTCTGCGAGGTACGAATCCGAACCGGCCAGACGGAGGTCGCTGTCTTCACAGCTTACGAACCTGAGGAGTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9821.36 Da
• Isoelectric Point: 10.0901

>AT142311 WP_153448319.1 NZ_CP045700:135308-135574 [Vibrio sp. SM1977]
MATKTAPINMRVEPQVRNVIDAAANLLKVDRSVFIQQAALAQARLVISNQRDFALDDVAFDAFEQALKVKPKANEGMTEL
LNRKAPWQ

Nucleotide

• Length: 267 bp

>AT142311 NZ_CP060666:2085237-2085295 [Salmonella enterica]
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTACATGTGCAAAGCATGAAATTGGCCTCA