Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2068593..2068738 | Replicon | chromosome |
| Accession | NZ_CP045694 | ||
| Organism | Klebsiella pneumoniae strain TK421 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2068629..2068731 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2068593..2068738 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GHA50_RS11455 | 2063723..2065783 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| GHA50_RS11460 | 2065787..2066446 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| GHA50_RS11465 | 2066525..2066755 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| GHA50_RS11470 | 2066868..2067242 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| GHA50_RS11475 | 2067246..2068115 | + | 870 | WP_023280292.1 | copper homeostasis membrane protein CopD | - |
| GHA50_RS11480 | 2068132..2068470 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2068593..2068738 | - | 146 | - | - | Antitoxin |
| - | 2068629..2068731 | + | 103 | - | - | Toxin |
| GHA50_RS11485 | 2069107..2069250 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| GHA50_RS11490 | 2069355..2070323 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| GHA50_RS11495 | 2070480..2071133 | + | 654 | WP_023280291.1 | protein-serine/threonine phosphatase | - |
| GHA50_RS11500 | 2071130..2071321 | - | 192 | WP_002911395.1 | YebW family protein | - |
| GHA50_RS11505 | 2071419..2071658 | - | 240 | WP_002911393.1 | YebV family protein | - |
| GHA50_RS11510 | 2071774..2073207 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T142291 NZ_CP045694:2068629-2068731 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT142291 NZ_CP045694:c2068738-2068593 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
