142282

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/HTH_10(toxin)
Location 1139047..1140026 Replicon chromosome
Accession NZ_CP045687
Organism Sulfolobus sp. E5-1-F

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GFS03_RS05540 Protein ID WP_153422879.1
Coordinates 1139412..1140026 (+) Length 205 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GFS03_RS05535 Protein ID WP_153422878.1
Coordinates 1139047..1139394 (+) Length 116 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFS03_RS05505 (GFS03_05505) 1134585..1135427 + 843 WP_153422872.1 KaiC domain-containing protein -
GFS03_RS05510 (GFS03_05510) 1135464..1136660 + 1197 WP_153422873.1 MFS transporter -
GFS03_RS05515 (GFS03_05515) 1136605..1137540 + 936 WP_153422874.1 dipeptidase -
GFS03_RS05520 (GFS03_05520) 1137840..1138271 + 432 WP_153422875.1 universal stress protein -
GFS03_RS05525 (GFS03_05525) 1138264..1138653 - 390 WP_153422876.1 metal-sulfur cluster assembly factor -
GFS03_RS05530 (GFS03_05530) 1138710..1138979 + 270 WP_238699222.1 C2H2-type zinc finger protein -
GFS03_RS05535 (GFS03_05535) 1139047..1139394 + 348 WP_153422878.1 DUF488 domain-containing protein Antitoxin
GFS03_RS05540 (GFS03_05540) 1139412..1140026 + 615 WP_153422879.1 helix-turn-helix domain-containing protein Toxin
GFS03_RS05545 (GFS03_05545) 1140099..1140374 - 276 WP_153422880.1 hypothetical protein -
GFS03_RS05550 (GFS03_05550) 1140499..1141014 + 516 WP_153422881.1 hemerythrin domain-containing protein -
GFS03_RS05555 (GFS03_05555) 1141119..1141877 + 759 WP_153422882.1 plastocyanin/azurin family copper-binding protein -
GFS03_RS05560 (GFS03_05560) 1141881..1142225 + 345 WP_153422883.1 hypothetical protein -
GFS03_RS05565 (GFS03_05565) 1142206..1142451 - 246 WP_238699224.1 hypothetical protein -
GFS03_RS05570 (GFS03_05570) 1143039..1143638 + 600 WP_153422884.1 DUF2249 domain-containing protein -
GFS03_RS05575 (GFS03_05575) 1143699..1144889 + 1191 WP_153422885.1 amidohydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Bacterioopsin activator-type, HTH domain

(145-197)

Antitoxin

Protein of unknown function DUF488

(3-108)


Sequences

Toxin        


Download         Length: 205 a.a.        Molecular weight: 23300.44 Da        Isoelectric Point: 8.9734

>T142282 WP_153422879.1 NZ_CP045687:1139412-1140026 [Sulfolobus sp. E5-1-F]
MFKSPFEVTILIEEHPCEVMKIISSPGLKGVVDNVKLGDNTTDHIVLFEKEVQKDDLIKLKSHSTKVLRLNDNKVWVRTY
GCAVCKILYISNVVVEKIKVVKERTLLYTLLVPNTMALKEFLGNLTSQGIKFTVLSTSEISSNELTDRQMEILKLAYKMG
YFDDDRRVTLTELAMQLGISTPTLEEILRRALRKVVKYYLDKVG

Download         Length: 615 bp

>T142282 NZ_CP060588:c1394581-1394090 [Bifidobacterium longum]
ATGACCGACGTTTCCATGCAGCGTATTTTGCTCGATACCAACGTACTGTTGGACTATTTGCTCCATCGCGATGATCACGC
CAAGATGGCGGAAGCGGTTATGGAACTTGGCGCGAAGAACAACATTACGTTGTTGTGCGCGTCATTGTCGCTGAAGGATA
TCGCATACCTATCATCATCGGCGATTCGTAGGGAATTCAAACCGAATGAATCGGAAGTGGAGAATTTCACTCGCGGCTTT
CTGTCGTCACGGGTGCCATGGCGTTGTATCGAGCAGGTGAAGGAGATGTGTGACATCGTCGCTGTCGATGAGTCGACATG
TGATAAGGCTTTTTCCCTGCAAAAACGGCATCGGGATTTTGAAGATGATCTGATCATCGTTGCCGCGCAACAATCCGGTG
CCAACTGTGTGGTCACATCGGATGCCGAATTAATCAGTCATTTTCCCGAATATTGCAAAACACCGGCTGAAATCGTGGCG
GCGCTGGAATAA

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 13566.83 Da        Isoelectric Point: 10.0387

>AT142282 WP_153422878.1 NZ_CP045687:1139047-1139394 [Sulfolobus sp. E5-1-F]
MIRIKRIYDPIEKDDGVRILVDRLWPRGVSKDKVDLWLKDIAPSDELRKWFSHDASKWDEFKKKYFEELDANPKIGVLFQ
LVKKGGNITLLYASKSPYNNAVALKEYLEKKILKQ

Download         Length: 348 bp

>AT142282 NZ_CP060588:c1394943-1394581 [Bifidobacterium longum]
ATGACCATGGTCCAAATGAACGTTCGCATTGATGCGAAACTGAAGAACGAGGTCGAAGAAGTCCTCAAGGGCAAAGGCGT
ATCGGTGAGTGACGTAATCCGGTCGCTGTGGTTGTACATCGCCGACCGCAAGGAAGTGCCGGCATTGGAAACGACCGCCG
AAGAGCAAGCCCGCGAGGAGGAAAAGCAGCGCAAGCTGAAACTGATTCGAGAAGGTGCCGGATACGTACACAAGGAACTG
GTCAAGGCCGGACTGATCTCAGAAGACACCGACCTCATGGAAGGCCTTACCTACAAGCAGTTCCGCGACAAAATGTACGA
CGAGCAACTTGATGCGTATTACAACATGAAGAGGGCCGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References