Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1918237..1918382 Replicon chromosome
Accession NZ_CP045661
Organism Klebsiella pneumoniae strain SMU18037509

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1918273..1918375 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1918237..1918382 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFJ44_RS09065 1913367..1915427 + 2061 WP_004151449.1 oligopeptidase B -
GFJ44_RS09070 1915431..1916090 - 660 WP_002911407.1 exodeoxyribonuclease X -
GFJ44_RS09075 1916169..1916399 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GFJ44_RS09080 1916512..1916886 + 375 WP_004151448.1 CopC domain-containing protein YobA -
GFJ44_RS09085 1916890..1917759 + 870 WP_153517860.1 copper homeostasis membrane protein CopD -
GFJ44_RS09090 1917776..1918114 + 339 WP_016529031.1 YebY family protein -
- 1918237..1918382 - 146 - - Antitoxin
- 1918273..1918375 + 103 - - Toxin
GFJ44_RS09095 1918751..1918894 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
GFJ44_RS09100 1918999..1919967 - 969 WP_074185275.1 DUF535 family protein -
GFJ44_RS09105 1920124..1920777 + 654 WP_032447686.1 protein-serine/threonine phosphatase -
GFJ44_RS09110 1920774..1920965 - 192 WP_002911395.1 YebW family protein -
GFJ44_RS09115 1921063..1921302 - 240 WP_002911393.1 YebV family protein -
GFJ44_RS09120 1921418..1922851 - 1434 WP_032447684.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T142260 NZ_CP045661:1918273-1918375 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT142260 NZ_CP045661:c1918382-1918237 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References