Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 6501912..6502438 Replicon chromosome
Accession NZ_CP045643
Organism Streptomyces fagopyri strain QMT-28

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GFH48_RS28065 Protein ID WP_055511941.1
Coordinates 6501912..6502169 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GFH48_RS28070 Protein ID WP_153290897.1
Coordinates 6502166..6502438 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFH48_RS28040 6497287..6498162 + 876 WP_153290892.1 hypothetical protein -
GFH48_RS28045 6498210..6498848 - 639 WP_153290893.1 hypothetical protein -
GFH48_RS28050 6498841..6499110 - 270 WP_153290894.1 hypothetical protein -
GFH48_RS28055 6499339..6499749 + 411 WP_153290895.1 hypothetical protein -
GFH48_RS28060 6499746..6501872 + 2127 WP_153290896.1 tetratricopeptide repeat protein -
GFH48_RS28065 6501912..6502169 - 258 WP_055511941.1 Txe/YoeB family addiction module toxin Toxin
GFH48_RS28070 6502166..6502438 - 273 WP_153290897.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GFH48_RS28075 6502785..6503579 + 795 Protein_5525 phage resistance protein -
GFH48_RS28080 6503575..6504561 + 987 Protein_5526 ATP-dependent helicase -
GFH48_RS28085 6505202..6506248 + 1047 WP_153290898.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-71)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10132.59 Da        Isoelectric Point: 9.8613

>T142246 WP_055511941.1 NZ_CP045643:c6502169-6501912 [Streptomyces fagopyri]
VRSVHFDPAGWEDFLFWLGSDRAMARRITRLIAEIQRTPFTGIGKPEPLKGDLSGYWSRRIDDEHRLVYRVDEKEVKILK
ARYHY

Download         Length: 258 bp

>T142246 NZ_CP060491:863228-863545 [Staphylococcus aureus]
ATGAATTGGGAAATTAAAGATTTGATGTGTGATATTGAAGTGATAAAAGAAAAAATCAATGATGTAGCTATCAAACATGG
TTGGTTTGTTGAAGATAAATTTGTCAAAAATGAATTAGAAACAAAACAGGAACATATTAATTTTTCTGCTAGCTATTTAG
AACATCGTATACAAAATGAACATACAGTTGAGTTATTACAGGTGTACTTAAAAGAATTCGGTGAACTTATACAAAAGTTT
CATGAAATAGAAAAAGCATCATCTGAGAACTTTGGCGAGGAATCAGATGACGCAAAGAAATTAAAAATTACAGAGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9856.06 Da        Isoelectric Point: 4.4978

>AT142246 WP_153290897.1 NZ_CP045643:c6502438-6502166 [Streptomyces fagopyri]
MTISASEARKDLFPLIKRVNDDHTPVRISSKSGDAVLMSAEDYDSWQETVYLLRSPANARSLMEAVARDRAGEAVVTKTM
AELEELAGDG

Download         Length: 273 bp

>AT142246 NZ_CP060491:863016-863225 [Staphylococcus aureus]
ATGAATAATGAACAAAAAGAAGTAATAGAACACGTGGTTTATCAACTTGAGTTAAGTATCATGAATAATTTTGAAAGTTA
TGAACACACGGAATATGTTGATGGTATTGAAGTGGTTTCAGAGATCAGTCCTGAAAAGCACTTAGAATTGATAATGAAAT
GGTGCGCACAAGAATTAAAGAATAATTTTCAATTAGAAAAAGGAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References