Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3766327..3767566 Replicon chromosome
Accession NZ_CP045631
Organism Roseibium aggregatum strain ZYF612

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GFK91_RS17200 Protein ID WP_229005875.1
Coordinates 3766327..3766947 (-) Length 207 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GFK91_RS17205 Protein ID WP_229003457.1
Coordinates 3766997..3767566 (-) Length 190 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFK91_RS17180 (GFK91_17085) 3762894..3763355 - 462 WP_023000201.1 Lrp/AsnC family transcriptional regulator -
GFK91_RS17185 (GFK91_17090) 3763460..3764926 + 1467 WP_229003455.1 aminotransferase class V-fold PLP-dependent enzyme -
GFK91_RS17190 (GFK91_17095) 3764943..3765731 + 789 WP_023000199.1 class II glutamine amidotransferase -
GFK91_RS17195 (GFK91_17100) 3765816..3766187 - 372 WP_229003456.1 STAS/SEC14 domain-containing protein -
GFK91_RS17200 (GFK91_17105) 3766327..3766947 - 621 WP_229005875.1 HD domain-containing protein Toxin
GFK91_RS17205 (GFK91_17110) 3766997..3767566 - 570 WP_229003457.1 helix-turn-helix transcriptional regulator Antitoxin
GFK91_RS17210 (GFK91_17115) 3767655..3768281 - 627 WP_229003458.1 DapH/DapD/GlmU-related protein -
GFK91_RS17215 (GFK91_17120) 3768681..3769514 + 834 WP_055659582.1 phosphonate ABC transporter ATP-binding protein -
GFK91_RS17220 (GFK91_17125) 3769573..3770487 + 915 WP_023000193.1 phosphonate ABC transporter substrate-binding protein -
GFK91_RS17225 (GFK91_17130) 3770670..3771518 + 849 WP_229003459.1 phosphonate ABC transporter, permease protein PhnE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(28-168)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-68)


Sequences

Toxin        


Download         Length: 207 a.a.        Molecular weight: 23150.39 Da        Isoelectric Point: 4.5596

>T142212 WP_229005875.1 NZ_CP045631:c3766947-3766327 [Roseibium aggregatum]
MTKTLPSLDLPEIPHTRLTGLLDFLQAAEQLKDTLRSGTTTGGRPESTAEHSWRLALMVLLFEPELKEIDLLKLLKLTLV
HDLGEAISGDVPAPLQTPGDDRQERERRDFLTLCEPLPGDVAGELTSLWDEYAAARTVEARLAKAFDKLETMLQHVLMPR
QAPSFYEFNLGYGRDRTDCSALTRQLRDEVDEMTRAMMTDAGREIA

Download         Length: 621 bp

>T142212 NZ_CP060459:42835-43161 [Xanthomonas citri pv. citri]
ATGATGCGGGGTGACTTTGTGACCATCGCCATGCAAGGCGACTTCGGAAAACCAAGGCCCGCTCTGGTGATCCAGGCCGA
CCAGTTTGACGCACACACCACCGTGACGGTGCTGCCGGTGACAAGCACGCTCGTTGCTGCGCCGCTGCTGCGTATTACCG
TTCATCCAAGTACCGACAATGGTTTGCAGAAGCCGTCTCAGGTGATGGTGGACAAGGCCATGACCGTGAAGCGTGACAAG
GTAGGTCGAGCCTTTGGGCGCGTAGACGCTGATGCGTTGGTGGAAATTGAGCGCTGCCTGGCCGTGTTCTTGGGCATCGC
TAAGTGA

Antitoxin


Download         Length: 190 a.a.        Molecular weight: 21634.60 Da        Isoelectric Point: 7.3890

>AT142212 WP_229003457.1 NZ_CP045631:c3767566-3766997 [Roseibium aggregatum]
MQTETAVLESSLGPSLRRWRVLNRVKQEALAHELGVSQTRISRWESGKSQPDDSDRAKITRLLRARPESAADKALLDLVS
RSAIPVHLVCDLTHRLLAMSVPRACEWRAPVNEFLNRPLWRFASEGIRATEHRLTDFGWFEPDAPDIVYRTEHVDFPEMT
IPESTIRISRLPLSDGRFARLVREEQDAA

Download         Length: 570 bp

>AT142212 NZ_CP060459:42620-42838 [Xanthomonas citri pv. citri]
ATGGCACACGTCAATTCACGAGTTCAAAAGCACCGCGACGCCCTGCGCATGGCAGGGCTGCGTCCGGTGCAAATTTGGGT
GCCGGACACACGGCGGCCTGACTTCGCCGAGGAATGCCGCCGTCAGTGTCGTCTTGCTGCACAAGCGGACATGGCGGATA
CCGACATGCAGCGCTTCATGGATGAGGCGCTAGCAGACATGGATGGCTGGACGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References