Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 129..667 Replicon plasmid unnamed2
Accession NZ_CP045624
Organism Roseibium aggregatum strain SDL044

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag GFK90_RS28980 Protein ID WP_228866822.1
Coordinates 129..422 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag GFK90_RS28985 Protein ID WP_228866823.1
Coordinates 419..667 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFK90_RS28980 (GFK90_28815) 129..422 - 294 WP_228866822.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GFK90_RS28985 (GFK90_28820) 419..667 - 249 WP_228866823.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
GFK90_RS28990 914..1078 - 165 WP_228866872.1 hypothetical protein -
GFK90_RS28995 (GFK90_28825) 1442..1702 + 261 WP_228866824.1 WGR domain-containing protein -
GFK90_RS29000 (GFK90_28830) 1790..2107 - 318 WP_075282947.1 DUF736 domain-containing protein -
GFK90_RS29005 (GFK90_28835) 2831..3760 - 930 WP_228866825.1 zincin-like metallopeptidase domain-containing protein -
GFK90_RS29010 (GFK90_28840) 4034..4219 - 186 WP_228866826.1 hypothetical protein -
GFK90_RS29015 (GFK90_28845) 4550..4945 - 396 WP_168693816.1 type II toxin-antitoxin system PemK/MazF family toxin -
GFK90_RS29020 (GFK90_28850) 4938..5204 - 267 WP_168693771.1 type II toxin-antitoxin system prevent-host-death family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..96518 96518


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin

Antitoxin ParD

(1-81)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11256.80 Da        Isoelectric Point: 6.3248

>T142206 WP_228866822.1 NZ_CP045624:c422-129 [Roseibium aggregatum]
MKVLVFSPAAEIDLEHIWDHSVEIWGLDQADRYLDEIRDACLGLASGDRRGRPVDVRAGYLKYATGVHMVYFRDHVDRLE
VIRILHQRQDVSRNLPT

Download         Length: 294 bp

>T142206 NZ_CP060453:c2889783-2889493 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9159.14 Da        Isoelectric Point: 5.7065

>AT142206 WP_228866823.1 NZ_CP045624:c667-419 [Roseibium aggregatum]
MARNTSVTLGDHFTGFISEQVQTGRYGSASDVVRAGLRLLEEHEAKVKALQDALIAGERSGEPQPFDFDDFKARKRAEYE
SR

Download         Length: 249 bp

>AT142206 NZ_CP060453:c2890049-2889771 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References