Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 50169..50815 Replicon plasmid unnamed3
Accession NZ_CP045620
Organism Roseibium aggregatum strain RF14

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GFC08_RS29630 Protein ID WP_228933627.1
Coordinates 50169..50576 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GFC08_RS29635 Protein ID WP_228933628.1
Coordinates 50573..50815 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFC08_RS29610 (GFC08_29415) 47386..47643 - 258 WP_228933625.1 DUF736 family protein -
GFC08_RS29615 47955..48686 - 732 WP_228933642.1 BID domain-containing protein -
GFC08_RS29620 48783..49613 - 831 Protein_50 Fic family protein -
GFC08_RS29625 (GFC08_29425) 49739..49945 - 207 WP_228933626.1 antitoxin VbhA family protein -
GFC08_RS29630 (GFC08_29430) 50169..50576 - 408 WP_228933627.1 type II toxin-antitoxin system VapC family toxin Toxin
GFC08_RS29635 (GFC08_29435) 50573..50815 - 243 WP_228933628.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GFC08_RS29640 (GFC08_29440) 51483..52454 - 972 WP_228933629.1 hypothetical protein -
GFC08_RS29645 (GFC08_29445) 52598..52807 - 210 Protein_55 transposase -
GFC08_RS29650 (GFC08_29450) 53021..53512 - 492 WP_228933630.1 ParB/Srx family N-terminal domain-containing protein -
GFC08_RS29655 (GFC08_29455) 53595..54458 - 864 WP_228933631.1 DUF932 domain-containing protein -
GFC08_RS29660 (GFC08_29460) 55093..55296 - 204 WP_228933632.1 trans-acting factor B -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..125470 125470


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-50)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14983.05 Da        Isoelectric Point: 4.7381

>T142204 WP_228933627.1 NZ_CP045620:c50576-50169 [Roseibium aggregatum]
MIYVLDTNVISAARRAERAPKVAAWLSDKAEETLYVSVVTLGEIERGIRLQERRNADFAKDLRLWLDRTVSMFGDRLLEF
TASDALCWGELSARIGHNGADLMIAAQALTRNGWVVTGNASDFEPTGVQLVDPFV

Download         Length: 408 bp

>T142204 NZ_CP060453:99890-100189 [Xanthomonas citri pv. citri]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGGGCACGTTGAGCAATTGATCGAACACCCGGACAGCGGAAGCCGACCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACGTCATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9013.23 Da        Isoelectric Point: 9.7747

>AT142204 WP_228933628.1 NZ_CP045620:c50815-50573 [Roseibium aggregatum]
MISLQDAKNRFSAVVEAAMAGRPQEVSRRGKPAVVVISAEEYYRLVREAKGRRESFADHVLSFPGEGFERSKVTPRDVEF

Download         Length: 243 bp

>AT142204 NZ_CP060453:99645-99902 [Xanthomonas citri pv. citri]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACGGCACCGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References