Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 29108..29646 Replicon plasmid unnamed2
Accession NZ_CP045619
Organism Roseibium aggregatum strain RF14

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag GFC08_RS28335 Protein ID WP_228866822.1
Coordinates 29353..29646 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag GFC08_RS28330 Protein ID WP_228866823.1
Coordinates 29108..29356 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFC08_RS28290 (GFC08_28090) 24311..25186 + 876 WP_228933501.1 hypothetical protein -
GFC08_RS28295 (GFC08_28095) 25183..25533 + 351 WP_228933503.1 hypothetical protein -
GFC08_RS28300 (GFC08_28100) 25424..25981 + 558 WP_228933505.1 tyrosine-type recombinase/integrase -
GFC08_RS28305 (GFC08_28105) 25978..26982 + 1005 WP_228933507.1 tyrosine-type recombinase/integrase -
GFC08_RS28310 (GFC08_28110) 27350..27649 + 300 WP_228933509.1 DUF736 family protein -
GFC08_RS28315 27812..27985 + 174 Protein_28 DUF736 family protein -
GFC08_RS28320 (GFC08_28120) 28073..28333 - 261 WP_228866824.1 WGR domain-containing protein -
GFC08_RS28325 28697..28861 + 165 WP_228866872.1 hypothetical protein -
GFC08_RS28330 (GFC08_28125) 29108..29356 + 249 WP_228866823.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
GFC08_RS28335 (GFC08_28130) 29353..29646 + 294 WP_228866822.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GFC08_RS28340 (GFC08_28135) 29678..31597 - 1920 WP_228933511.1 Ti-type conjugative transfer system protein TraG -
GFC08_RS28345 (GFC08_28140) 31518..31793 - 276 WP_168693817.1 conjugal transfer protein TraD -
GFC08_RS28350 (GFC08_28145) 31822..32073 - 252 WP_228933512.1 TraC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..249751 249751


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin

Antitoxin ParD

(1-81)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11256.80 Da        Isoelectric Point: 6.3248

>T142203 WP_228866822.1 NZ_CP045619:29353-29646 [Roseibium aggregatum]
MKVLVFSPAAEIDLEHIWDHSVEIWGLDQADRYLDEIRDACLGLASGDRRGRPVDVRAGYLKYATGVHMVYFRDHVDRLE
VIRILHQRQDVSRNLPT

Download         Length: 294 bp

>T142203 NZ_CP060448:42351-42677 [Xanthomonas citri pv. citri]
ATGATGCGGGGTGACTTTGTGACCATCGCCATGCAAGGCGACTTCGGAAAACCAAGGCCCGCTCTGGTGATCCAGGCCGA
CCAGTTTGACGCACACACCACCGTGACGGTGCTGCCGGTGACAAGCACGCTCGTTGCTGCGCCGCTGCTGCGTATTACCG
TTCATCCAAGTACCGACAATGGTTTGCAGAAGCCGTCTCAGGTGATGGTGGACAAGGCCATGACCGTGAAGCGTGACAAG
GTAGGTCGAGCCTTTGGGCGCGTAGACGCTGATGCGTTGGTGGAAATTGAGCGCTGCCTGGCCGTGTTCTTGGGCATCGC
TAAGTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9159.14 Da        Isoelectric Point: 5.7065

>AT142203 WP_228866823.1 NZ_CP045619:29108-29356 [Roseibium aggregatum]
MARNTSVTLGDHFTGFISEQVQTGRYGSASDVVRAGLRLLEEHEAKVKALQDALIAGERSGEPQPFDFDDFKARKRAEYE
SR

Download         Length: 249 bp

>AT142203 NZ_CP060448:42136-42354 [Xanthomonas citri pv. citri]
ATGGCACACGTCAATTCACGAGTTCAAAAGCACCGCGACGCCCTGCGCATGGCAGGGCTGCGTCCGGTGCAAATTTGGGT
GCCGGACACACGGCGGCCTGACTTCGCCGAGGAATGCCGCCGTCAGTGTCGTCTTGCTGCACAAGCGGACATGGCGGATA
CCGACATGCAGCGCTTCATGGATGAGGCGCTAGCAGACATGGATGGCTGGACGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References