Detailed information of TA system TA142202

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/-
• Location: 5816209..5817448
• Replicon: chromosome
• Accession: NZ_CP045617
• Organism: Roseibium aggregatum strain RF14

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: GFC08_RS26685
• Protein ID: WP_228932973.1
• Coordinates: 5816828..5817448 (+)
• Length: 207 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: GFC08_RS26680
• Protein ID: WP_228930822.1
• Coordinates: 5816209..5816778 (+)
• Length: 190 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GFC08_RS26660 (GFC08_26470)	5812258..5813106	-	849	WP_023000192.1	phosphonate ABC transporter, permease protein PhnE	-
GFC08_RS26665 (GFC08_26475)	5813288..5814202	-	915	WP_023000193.1	phosphonate ABC transporter substrate-binding protein	-
GFC08_RS26670 (GFC08_26480)	5814261..5815094	-	834	WP_055659582.1	phosphonate ABC transporter ATP-binding protein	-
GFC08_RS26675 (GFC08_26485)	5815494..5816120	+	627	WP_055659209.1	DapH/DapD/GlmU-related protein	-
GFC08_RS26680 (GFC08_26490)	5816209..5816778	+	570	WP_228930822.1	helix-turn-helix transcriptional regulator	Antitoxin
GFC08_RS26685 (GFC08_26495)	5816828..5817448	+	621	WP_228932973.1	HD domain-containing protein	Toxin
GFC08_RS26690 (GFC08_26500)	5817588..5817959	+	372	WP_023000198.1	STAS/SEC14 domain-containing protein	-
GFC08_RS26695 (GFC08_26505)	5818058..5818846	-	789	WP_023000199.1	class II glutamine amidotransferase	-
GFC08_RS26700 (GFC08_26510)	5818863..5820329	-	1467	WP_228930823.1	aminotransferase class V-fold PLP-dependent enzyme	-
GFC08_RS26705 (GFC08_26515)	5820434..5820895	+	462	WP_023000201.1	Lrp/AsnC family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HD domain (28-168)

Antitoxin

• Cro/C1-type helix-turn-helix domain (16-68)

Sequences

Toxin

Protein

• Length: 207 a.a.
• Molecular weight: 23062.27 Da
• Isoelectric Point: 4.6200

>T142202 WP_228932973.1 NZ_CP045617:5816828-5817448 [Roseibium aggregatum]
MTKTPPSLDLPEISHTRLTGLLDFLQAAEQLKDTLRSGSTSGGRPESTAEHSWRLALMVLLFEPELKEIDLLKLLKLTLV
HDLGEAISGDVPAPLQTPGDDRQERERRDFLTLCEPLPGDVAGELTSLWDEYAAARTVEARLAKAFDKLETMLQHVLMPR
QAPSFYEFNLGYGRDRTDCSALTRQLRDEVDELTRIMMTGAGREIA

Nucleotide

• Length: 621 bp

>T142202 NZ_CP060448:32051-32452 [Xanthomonas citri pv. citri]
ATGAAGCGGTACATGCTTGATACCAACACCGTGAGCCATCTCGTCAAGAGCCATCCGGCTGTCTCTCGACGGGTCATTGA
AGTGCCTATGACTGCGCTATGTATGTCCGCAATTACCGGTGGGGAGCTGATGTTCGGCTTGGCTAAGGTGCCAGACGCCA
AACGCCTTCAGCAAGCCGTCATGGAACTCCTGCGGCGCGTGGATGTGCTGCCTTGGGATGGCGCGGTAATGGAGCGTTAC
GGAAGCGTAAGAGCGGACCTAGAAAAGCAAGGTAAAGCGCTTGGGTCGCTCGACATGCTTATCGCAGCACATGCACTGGA
AACGGATTCTGTCCTCGTTACCAATGACGCCGCATTTAGTCGTGTTGTTGGTTTGACCGTGGAAGATTGGACACGCAGCT
AA

Antitoxin

Protein

• Length: 190 a.a.
• Molecular weight: 21647.62 Da
• Isoelectric Point: 7.4259

>AT142202 WP_228930822.1 NZ_CP045617:5816209-5816778 [Roseibium aggregatum]
MQTETVVLESSLGPSLRRWRVLNRVKQEALAHELGVSQTRISRWESGKSQPDDSDRAKITRLLRARPESAADKALLDLVS
RSAIPVHLVCDLTHRLLAMSVPRASEWRAPVSEFLNRPLWRFASEGIRATEHRLTDYGWFEPDAPDIVYRTEHVDFPEMT
IPESIIRISRLPLSDGRFARLVREEQDAA

Nucleotide

• Length: 570 bp

>AT142202 NZ_CP060448:31794-32054 [Xanthomonas citri pv. citri]
GTGAGCCAAGTTGCCAAGCTGTTCATCAATGGCCGCAGCCAGGCAGTCCGCTTGCCTGCCGCCTATCGCTTTACCGAGAA
AGAGGTTTTCATTCGCCAAGACCCGGAGACCGGTGACGTCATCCTGTCTCGGAAGCCTGCAACGTGGGAGGACTTCTTTA
TCGCACTCAAGAGCGCAGATGTGCCTGCTAATTTTCTAGATGCCGCCGAGCGCAATCAGGGCACGCAGGACCGTGATCCT
TTTGCGGGATGGCGCGAATGA