Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3482063..3482716 Replicon chromosome
Accession NZ_CP045560
Organism Acinetobacter nosocomialis strain AC1530

Toxin (Protein)


Gene name cptA Uniprot ID A0A2T7FQV3
Locus tag GD578_RS16780 Protein ID WP_025467795.1
Coordinates 3482063..3482452 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID N8SCE2
Locus tag GD578_RS16785 Protein ID WP_002049719.1
Coordinates 3482459..3482716 (-) Length 86 a.a.

Genomic Context

GD578_RS16790GD578_RS16765GD578_RS16770GD578_RS16775GD578_RS16780GD578_RS16785GD578_RS16795GD578_RS16800GD578_RS16805
Location: 3482906..3484078 (1173 bp)
Type: Others
Protein ID: WP_002049748.1
Location: 3477177..3479372 (2196 bp)
Type: Others
Protein ID: WP_025467793.1
Location: 3479560..3480126 (567 bp)
Type: Others
Protein ID: WP_002049725.1
Location: 3480210..3481295 (1086 bp)
Type: Others
Protein ID: WP_002049690.1
Location: 3482063..3482452 (390 bp)
Type: Toxin
Protein ID: WP_025467795.1
Location: 3482459..3482716 (258 bp)
Type: Antitoxin
Protein ID: WP_002049719.1
Location: 3484127..3485617 (1491 bp)
Type: Others
Protein ID: WP_002049727.1
Location: 3485799..3486176 (378 bp)
Type: Others
Protein ID: WP_002049717.1
Location: 3486195..3487202 (1008 bp)
Type: Others
Protein ID: WP_002049752.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GD578_RS167653477177..3479372-2196WP_025467793.1TRAP transporter large permease subunit-
GD578_RS167703479560..3480126-567WP_002049725.1rhombosortase-
GD578_RS167753480210..3481295-1086WP_002049690.1hypothetical protein-
GD578_RS167803482063..3482452-390WP_025467795.1hypothetical proteinToxin
GD578_RS167853482459..3482716-258WP_002049719.1succinate dehydrogenase assembly factor 2Antitoxin
GD578_RS167903482906..3484078+1173WP_002049748.1acyl-CoA dehydrogenase family protein-
GD578_RS167953484127..3485617-1491WP_002049727.1NAD(P)/FAD-dependent oxidoreductase-
GD578_RS168003485799..3486176-378WP_002049717.150S ribosomal protein L17-
GD578_RS168053486195..3487202-1008WP_002049752.1DNA-directed RNA polymerase subunit alpha-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15610.67 Da        Isoelectric Point: 10.0990

>T142129 WP_025467795.1 NZ_CP045560:c3482452-3482063 [Acinetobacter nosocomialis]
MINHLNFKLKYSRFAIIFQFFIGLSLAVLFYQLLPILWWLVTVSLLFISFIFFLKRPQLAQIAHLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFEGHKTLTSVIWFDQMPLSQWKQLKTLEKFY

Download         Length: 390 bp

>T142129 NZ_CP060401:c3236958-3236560 [Xenorhabdus nematophila]
ATGATATGGGTCAGCGCACAGGAAGTTATCGCTTTTCATGACCGAATATTACAACGGCTTCCCGGCGTTGCCGGAATGCC
CGATTCTGGTAGAGCTGAAGCGCTCATCTATCGGGTACAAAACCGTACACACCATGAAGGCATAACAGATATTTTTGAAC
TTGCAGCTACCTATTGGGCTGCTATCGCTCGTGGTCATATTTTCAATGATGGTAATAAGCGCACAGCGTTTTTCGTTACC
ATGACTTTTCTCTATCGTAACGGTATCAAGATCCGTGATAACGACAATACATTGGAAAACTTAACAGTAGATGCCGCTAC
GGGCGAGAAAACCGTTGACCAGTTGGCGCAGCACCTGCGCGAATTGGTGGACTATACTAACCCGAGCTGTAATCCATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10278.71 Da        Isoelectric Point: 4.7620

>AT142129 WP_002049719.1 NZ_CP045560:c3482716-3482459 [Acinetobacter nosocomialis]
MSEEMTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLK
HYVHG

Download         Length: 258 bp

>AT142129 NZ_CP060401:c3237176-3236955 [Xenorhabdus nematophila]
ATGCGTACATACACCTCAACTCAAGCCCGTGCCAACATCGCGGAAGTGTTGGACACAGCGGCTCACGGTGAACCTGTTGA
AATCACTCGTCGAGACGGTAGTTCAGCGGTCGTTATCAGTAGAGCTGAATTCGATAATTGGCAAAACGCTAAGCTGGATG
CAGAGTTCGATTCGATTATGCAACGTCATGGGCATACGATAGAGGCGCTGACAAATCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A2T7FQV3

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0Q1QI86

References