142129

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3482063..3482716 Replicon chromosome
Accession NZ_CP045560
Organism Acinetobacter nosocomialis strain AC1530

Toxin (Protein)


Gene name cptA Uniprot ID A0A2T7FQV3
Locus tag GD578_RS16780 Protein ID WP_025467795.1
Coordinates 3482063..3482452 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID N8SCE2
Locus tag GD578_RS16785 Protein ID WP_002049719.1
Coordinates 3482459..3482716 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GD578_RS16765 3477177..3479372 - 2196 WP_025467793.1 TRAP transporter large permease subunit -
GD578_RS16770 3479560..3480126 - 567 WP_002049725.1 rhombosortase -
GD578_RS16775 3480210..3481295 - 1086 WP_002049690.1 hypothetical protein -
GD578_RS16780 3482063..3482452 - 390 WP_025467795.1 hypothetical protein Toxin
GD578_RS16785 3482459..3482716 - 258 WP_002049719.1 succinate dehydrogenase assembly factor 2 Antitoxin
GD578_RS16790 3482906..3484078 + 1173 WP_002049748.1 acyl-CoA dehydrogenase family protein -
GD578_RS16795 3484127..3485617 - 1491 WP_002049727.1 NAD(P)/FAD-dependent oxidoreductase -
GD578_RS16800 3485799..3486176 - 378 WP_002049717.1 50S ribosomal protein L17 -
GD578_RS16805 3486195..3487202 - 1008 WP_002049752.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15610.67 Da        Isoelectric Point: 10.0990

>T142129 WP_025467795.1 NZ_CP045560:c3482452-3482063 [Acinetobacter nosocomialis]
MINHLNFKLKYSRFAIIFQFFIGLSLAVLFYQLLPILWWLVTVSLLFISFIFFLKRPQLAQIAHLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFEGHKTLTSVIWFDQMPLSQWKQLKTLEKFY

Download         Length: 390 bp

>T142129 NZ_CP060401:c3236958-3236560 [Xenorhabdus nematophila]
ATGATATGGGTCAGCGCACAGGAAGTTATCGCTTTTCATGACCGAATATTACAACGGCTTCCCGGCGTTGCCGGAATGCC
CGATTCTGGTAGAGCTGAAGCGCTCATCTATCGGGTACAAAACCGTACACACCATGAAGGCATAACAGATATTTTTGAAC
TTGCAGCTACCTATTGGGCTGCTATCGCTCGTGGTCATATTTTCAATGATGGTAATAAGCGCACAGCGTTTTTCGTTACC
ATGACTTTTCTCTATCGTAACGGTATCAAGATCCGTGATAACGACAATACATTGGAAAACTTAACAGTAGATGCCGCTAC
GGGCGAGAAAACCGTTGACCAGTTGGCGCAGCACCTGCGCGAATTGGTGGACTATACTAACCCGAGCTGTAATCCATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10278.71 Da        Isoelectric Point: 4.7620

>AT142129 WP_002049719.1 NZ_CP045560:c3482716-3482459 [Acinetobacter nosocomialis]
MSEEMTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLK
HYVHG

Download         Length: 258 bp

>AT142129 NZ_CP060401:c3237176-3236955 [Xenorhabdus nematophila]
ATGCGTACATACACCTCAACTCAAGCCCGTGCCAACATCGCGGAAGTGTTGGACACAGCGGCTCACGGTGAACCTGTTGA
AATCACTCGTCGAGACGGTAGTTCAGCGGTCGTTATCAGTAGAGCTGAATTCGATAATTGGCAAAACGCTAAGCTGGATG
CAGAGTTCGATTCGATTATGCAACGTCATGGGCATACGATAGAGGCGCTGACAAATCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2T7FQV3

Antitoxin

Source ID Structure
AlphaFold DB A0A0Q1QI86

References