142126

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 681028..682067 Replicon chromosome
Accession NZ_CP045554
Organism Pseudomonas sp. 14181154

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag GEV39_RS03145 Protein ID WP_173887527.1
Coordinates 681492..682067 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag GEV39_RS03140 Protein ID WP_125854783.1
Coordinates 681028..681492 (+) Length 155 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GEV39_RS03110 676494..677360 - 867 WP_173887524.1 A24 family peptidase -
GEV39_RS03115 677363..678571 - 1209 WP_173887525.1 type II secretion system F family protein -
GEV39_RS03120 678787..679197 + 411 WP_173887526.1 pilin -
GEV39_RS03130 679740..679859 + 120 Protein_593 Fic family protein -
GEV39_RS03135 680345..680572 + 228 WP_054903892.1 hypothetical protein -
GEV39_RS03140 681028..681492 + 465 WP_125854783.1 helix-turn-helix domain-containing protein Antitoxin
GEV39_RS03145 681492..682067 + 576 WP_173887527.1 PIN domain-containing protein Toxin
GEV39_RS03150 682824..683051 + 228 WP_054903892.1 hypothetical protein -
GEV39_RS03155 683357..683812 + 456 WP_173887528.1 GFA family protein -
GEV39_RS03160 683878..684099 - 222 WP_173887529.1 hypothetical protein -
GEV39_RS03165 684163..684861 + 699 WP_173887530.1 hypothetical protein -
GEV39_RS03170 684909..686294 - 1386 WP_173887531.1 gluconate:H+ symporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21976.44 Da        Isoelectric Point: 5.9330

>T142126 WP_173887527.1 NZ_CP045554:681492-682067 [Pseudomonas sp. 14181154]
MRHSPFTVIYDACVLYPAPLRDLLMHLALTGAYRARWSVQIHDEWTRNVLKNRSDLTKDQLDRTVVAMNRAVPDCLVNDY
EPLMLGLDLPDEDDRHVLAAAIKCGASVIVTYNLKDFPAEILKRFEIEALHPDVFLSDIWDLDQAAVLEAVQKQRASLKN
PRYTSRELLDILLKQRLPEIVKHLSSYELLI

Download         Length: 576 bp

>T142126 NZ_CP060401:c3033611-3033282 [Xenorhabdus nematophila]
ATGTATATACCAGACAAAGGTGACATTATTTCATTAAACTCTGATCCGAGTGCAGGCAAGGAAATCATGAAACGTCGTCC
TGCATTCGTTATATCTCGTAAAATGTTTAATGAGCACACTGGATTTGCTGTTGTAGTTCCAATCACGAGTACAGCGAGAG
GAATGAAGTTAGAAGTTATCTTACCCGAAGAAGTATCTGTTCAAGGCTCAATTCTCATTCATCAGGTAAAATCCTTAGAT
TTTTCGGAGCGTCAGGTCAAATTTATTGAGAAAGCGCCTCAATATATTATTGATAGAGTGACTGAGCTAACTAAGGCCAT
CATCTTATAG

Antitoxin


Download         Length: 155 a.a.        Molecular weight: 16986.52 Da        Isoelectric Point: 5.6434

>AT142126 WP_125854783.1 NZ_CP045554:681028-681492 [Pseudomonas sp. 14181154]
MTTADLARSILPDEKAIAAATESSRQIAAFVSTKLDIQRIELIDEAQQRQVVELPTFALRLLGDILNELALGNTVKVVPV
HAELTTQEAADMLNVSRPHLVKLLDEGQIPHTKTGSHRRIKFTDVMAFKAERDRVSQAAMEELAAQAQVLNMGY

Download         Length: 465 bp

>AT142126 NZ_CP060401:c3033868-3033611 [Xenorhabdus nematophila]
ATGACTGCTGTTGTCATTCGCCAATCTGGCGGTGCTAACATTGTTAGCATTCCAAAGGCCATAGTGAAAACACTTAATCT
GCATACTGGCTCAAAGCTAGAGCTATCTATTCAGGATAACAAAATTGTACTGACTCCAGTCGAAGAAGAGTTGACGCTGG
AATCGCTGTTAGCAGGAAGCCCTAAAGAATGTTTCAGAGTCACAGATGAGGATAGAGAGTGGCTTGAGGCTAATCCTGTT
GGTAAGGAAGTGATTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References