142114

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3860057..3860940 Replicon chromosome
Accession NZ_CP045551
Organism Pseudomonas putida strain 15420352

Toxin (Protein)


Gene name - Uniprot ID A0A2I0CF56
Locus tag GEV41_RS18015 Protein ID WP_004573725.1
Coordinates 3860057..3860494 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID I7C3Q7
Locus tag GEV41_RS18020 Protein ID WP_003250525.1
Coordinates 3860491..3860940 (-) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GEV41_RS18000 3856358..3857587 - 1230 WP_173880761.1 acyl-CoA dehydrogenase -
GEV41_RS18005 3857728..3858651 + 924 WP_004573723.1 LysR family transcriptional regulator -
GEV41_RS18010 3858845..3859999 + 1155 WP_060537721.1 aminotransferase class V-fold PLP-dependent enzyme -
GEV41_RS18015 3860057..3860494 - 438 WP_004573725.1 RES family NAD+ phosphorylase Toxin
GEV41_RS18020 3860491..3860940 - 450 WP_003250525.1 DUF2384 domain-containing protein Antitoxin
GEV41_RS18025 3861083..3861736 - 654 WP_004573726.1 oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB -
GEV41_RS18030 3861840..3862763 + 924 WP_004573727.1 LysR family transcriptional regulator -
GEV41_RS18035 3862812..3863642 + 831 WP_003250518.1 AraC family transcriptional regulator -
GEV41_RS18040 3863694..3864278 + 585 WP_004573728.1 LysE family transporter -
GEV41_RS18045 3864318..3865517 - 1200 WP_003250514.1 sugar transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-138)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(33-91)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15983.24 Da        Isoelectric Point: 6.0704

>T142114 WP_004573725.1 NZ_CP045551:c3860494-3860057 [Pseudomonas putida]
VILWRISAYTDLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSAHPELTRTLGNRFLDDGSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLF

Download         Length: 438 bp

>T142114 NZ_CP060399:3831414-3831665 [Xanthomonas hortorum pv. vitians]
ATGGACACCATCACCTACAGCGCCGCGCGTGCCTCTCTGGCCGACACCATGGACCGTGTCGTCAATGACCACGAGCCGGT
GATCATCACGCGCAGCGGTGAGCGCGCCGTGGTCATGGTGTCGCTGGAAGATTACAAGGCCATGGAAGAGACCGCCTACC
TGTTGCGCAGCCCGAAGAGTGCGCAACGGCTGCTGGAATCCATTGCCCAGCTTGAGGCCGGTCGCGGCAAGGAACGGGAA
CTGGCTGAGTGA

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 16956.46 Da        Isoelectric Point: 5.7258

>AT142114 WP_003250525.1 NZ_CP045551:c3860940-3860491 [Pseudomonas putida]
MLAEVLRDNGYHEYRARLQALLDIPELASDFEIHTRITDGFAATWLVKLTERGVLTPVERDQIIPLRTLKSRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGYGL

Download         Length: 450 bp

>AT142114 NZ_CP060399:3831662-3831919 [Xanthomonas hortorum pv. vitians]
GTGATTCTGCAGTTTGCTGACAATGCCTGGGAGGACTACCTCTACTGGCAACAGACCGACAAGAAGATGCTCAAACGCAT
CAACGAGTTGATCAAGGCCATTCAGCGCGATCCTTTCCAGGGCATCGGCAAACCCGAACCGTTGCGCCATGCGCTGGCGG
GCTACTGGTCACGCCGCATCAACGACGAACACCGGATCGTTTACAAGGCCGAGAACGGCATCCTGTTGATTGCTCAGGCG
CGCTACCACTACGGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I0CF56

Antitoxin

Source ID Structure
AlphaFold DB I7C3Q7

References