142110

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1641905..1642467 Replicon chromosome
Accession NZ_CP045550
Organism Venatoribacter cucullus strain ASxS5

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GAY96_RS07815 Protein ID WP_228346565.1
Coordinates 1642186..1642467 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GAY96_RS07810 Protein ID WP_228346566.1
Coordinates 1641905..1642189 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GAY96_RS07800 (GAY96_07745) 1638306..1640978 + 2673 WP_265573088.1 nitrate reductase -
GAY96_RS07805 (GAY96_07750) 1640975..1641802 + 828 WP_265573089.1 uroporphyrinogen-III C-methyltransferase -
GAY96_RS07810 (GAY96_07755) 1641905..1642189 + 285 WP_228346566.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
GAY96_RS07815 (GAY96_07760) 1642186..1642467 + 282 WP_228346565.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GAY96_RS07820 (GAY96_07765) 1642496..1642798 - 303 WP_265573090.1 hypothetical protein -
GAY96_RS07825 (GAY96_07770) 1642892..1643464 - 573 WP_265573091.1 DNA-3-methyladenine glycosylase I -
GAY96_RS07830 (GAY96_07775) 1643464..1644117 - 654 WP_265573092.1 DUF938 domain-containing protein -
GAY96_RS07835 (GAY96_07780) 1644328..1646064 + 1737 WP_265573093.1 proline--tRNA ligase -
GAY96_RS07840 (GAY96_07785) 1646058..1646705 + 648 WP_265573094.1 lytic transglycosylase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(1-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-75)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10834.60 Da        Isoelectric Point: 5.0893

>T142110 WP_228346565.1 NZ_CP045550:1642186-1642467 [Venatoribacter cucullus]
MIAWEEESLNDREKIFEYLYQFNPIAAEKTDDLIVAKVETLIAQPLMGVERVGIRGRLLIIPDVSLMVVYFFDGSTIRIL
RVLHQKQQYPHSN

Download         Length: 282 bp

>T142110 NZ_CP060398:c1501623-1501342 [Synechococcus sp. CBW1002]
ATGCTCTTTGAGCTGGCCTTTCACCCGGAAGCCCTTCGGGAGTGGCGGAAGCTGACGCCAGGAATCCGGGAGCAGTTCAT
GAACAAGTTGGCCGGGCGGCTGACTGAGCCCAGGATCCCCGCGAGCAAATTGCGTGGATCCTCCAACCGCTACAAGATCA
AGTTGCGGGCCGCCGGGTACCGTCTGGTCTACGAGGTGCGTGACCATGAGCTCCTCGTCCTTGTCGTGGCGGTGGGCAAG
CGGGAGCACAATGTTGTCGACCAGCGTGCCGATCAGCGCTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10769.17 Da        Isoelectric Point: 7.1689

>AT142110 WP_228346566.1 NZ_CP045550:1641905-1642189 [Venatoribacter cucullus]
METRIQFRIAEDTKRLAQQLAESQGRTLSDACRELAEQMAEQQRKVLSHDAWLTEQVTQAFAKLDSGQAVFVEHNAAQAA
MEERKAIIRKRLNQ

Download         Length: 285 bp

>AT142110 NZ_CP060398:c1501867-1501613 [Synechococcus sp. CBW1002]
ATGGCCCACCGCGTACTCACCGAGACAGCGGTGAGCATCTCGGAACACAAGAAAAACCCCATGGCCACCGTGGCGGCAGG
AGAGGGAATGGCCGTCGCGGTGCTCAACCGCAACGAGCCGGCCTTCTACTGCGTGCCGGCCAGGGCTTACGAAGAACTGA
TGGATCTGGTGGACGACCTGGAGCTGGGCCGCATCGCCGATGCCCGGCTGACGGACGGCCAGGAGCCTGTGCGGGTCAGC
CTCGATGCTCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References