Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB(toxin)
Location 846661..847060 Replicon chromosome
Accession NZ_CP045530
Organism Limosilactobacillus pontis strain LP475

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag LP475_RS04170 Protein ID WP_057808317.1
Coordinates 846661..846918 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag LP475_RS04175 Protein ID WP_152936730.1
Coordinates 846911..847060 (-) Length 50 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP475_RS04130 841745..842236 + 492 WP_057808310.1 ECF transporter S component -
LP475_RS04140 842406..842969 - 564 WP_083479949.1 RNA 2'-phosphotransferase -
LP475_RS04145 843065..844018 + 954 WP_057808312.1 3-hydroxyacyl-CoA dehydrogenase family protein -
LP475_RS04150 844022..844312 + 291 WP_057808313.1 hypothetical protein -
LP475_RS04155 844365..845213 - 849 WP_057808314.1 aldo/keto reductase -
LP475_RS04160 845709..846086 + 378 WP_057808315.1 carboxymuconolactone decarboxylase family protein -
LP475_RS04165 846153..846500 + 348 WP_057808316.1 helix-turn-helix transcriptional regulator -
LP475_RS04170 846661..846918 - 258 WP_057808317.1 Txe/YoeB family addiction module toxin Toxin
LP475_RS04175 846911..847060 - 150 WP_152936730.1 hypothetical protein Antitoxin
LP475_RS04180 847147..847546 - 400 Protein_781 type II toxin-antitoxin system death-on-curing family toxin -
LP475_RS04185 847548..847793 - 246 WP_057808320.1 hypothetical protein -
LP475_RS04190 847899..848807 - 909 WP_057808321.1 L-lactate dehydrogenase -
LP475_RS04195 848940..850136 - 1197 WP_057808322.1 tryptophan synthase subunit beta -
LP475_RS04200 850400..851539 - 1140 WP_057808323.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10380.80 Da        Isoelectric Point: 8.2579

>T142102 WP_057808317.1 NZ_CP045530:c846918-846661 [Limosilactobacillus pontis]
MIKCWSDDAWNDYMYWHDQGQKKVIKKINKSIRDIDRHPFEGLGKPEPLQYNLSGKWSRRINLEHCLIYTADKENIYIYS
CRDHY

Download         Length: 258 bp

>T142102 NZ_CP060397:2798382-2798606 [Synechococcus sp. CBW1004]
GTGGGCTCCACACCGGTTCTCAAGCCCTCGGAGGTGGTCGACATCCTGCGGACACTGGGTTTCGAGCTTGTCCGTCAACG
CGGATCGCATCTGCAGTTCCGCGATGCCCGTGGGCGCGGCACCACTGTTCCAGCCCATCAGGGTCGCGACATCGCCCCAC
CGCTGCTTCGTCAGATCGCCAAGGACATCGGCATGACCGTGGAGGAGTTCCTCCGCCACCGTTGA

Antitoxin


Download         Length: 50 a.a.        Molecular weight: 5698.22 Da        Isoelectric Point: 4.2493

>AT142102 WP_152936730.1 NZ_CP045530:c847060-846911 [Limosilactobacillus pontis]
MSKDNYDAIMETLSVNSNDYLMRKLARGDEQFKNGGFKQHELITEDDND

Download         Length: 150 bp

>AT142102 NZ_CP060397:2798167-2798379 [Synechococcus sp. CBW1004]
ATGCGCACGTACTCGGCTGTGATCGAACGCTGCAGCGAGACCGGTCTGCTTGTGGGTCATGTGCCTGGCTTCCCCGGTGC
TCACAGCCAGGGGGCGACGCTCGATGAGCTGCAGGCCAACCTCCAGGAGGTGATCGCCATGCTGCTGGAGGACGGCGAGC
CGAACCTGGAGAGCGACTTCGTCGGCCTGCAGCAGATTGTGGTTCCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References