Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2580637..2580871 | Replicon | chromosome |
| Accession | NZ_CP045522 | ||
| Organism | Shigella flexneri strain 5908.2 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2580638..2580741 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2580637..2580871 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GE167_RS13065 | 2576724..2577347 | - | 624 | WP_152030437.1 | DUF4376 domain-containing protein | - |
| GE167_RS23875 | 2577298..2577465 | - | 168 | Protein_2576 | phage tail protein | - |
| GE167_RS23880 | 2577467..2577847 | - | 381 | Protein_2577 | IS66-like element accessory protein TnpA | - |
| GE167_RS13080 | 2577917..2579066 | + | 1150 | Protein_2578 | IS3 family transposase | - |
| GE167_RS13085 | 2579183..2579464 | + | 282 | WP_005127484.1 | excisionase | - |
| GE167_RS13090 | 2579430..2580506 | + | 1077 | WP_025758140.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2580637..2580871 | + | 235 | - | - | Antitoxin |
| - | 2580638..2580741 | - | 104 | - | - | Toxin |
| GE167_RS13095 | 2580899..2581240 | - | 342 | WP_000976476.1 | YebY family protein | - |
| GE167_RS13100 | 2581253..2582125 | - | 873 | Protein_2582 | copper homeostasis membrane protein CopD | - |
| GE167_RS13105 | 2582129..2582503 | - | 375 | WP_025758141.1 | CopC domain-containing protein YobA | - |
| GE167_RS13110 | 2582642..2582872 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| GE167_RS13115 | 2582974..2583630 | + | 657 | WP_000011667.1 | carbon-nitrogen hydrolase family protein YobB | - |
| GE167_RS13120 | 2583654..2584316 | + | 663 | WP_000944269.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T142036 NZ_CP045522:c2580741-2580638 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT142036 NZ_CP045522:2580637-2580871 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT
