Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 3483697..3484478 Replicon chromosome
Accession NZ_CP045508
Organism Desulfolutivibrio sulfoxidireducens strain DSM 107105

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag GD604_RS15140 Protein ID WP_176638012.1
Coordinates 3483697..3484197 (-) Length 167 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag GD604_RS15145 Protein ID WP_176632225.1
Coordinates 3484194..3484478 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GD604_RS15105 3478721..3479230 + 510 WP_176632217.1 OmpH family outer membrane protein -
GD604_RS15110 3479320..3479787 + 468 WP_176632218.1 3-hydroxyacyl-ACP dehydratase FabZ -
GD604_RS15115 3479839..3481623 - 1785 WP_176638011.1 GAF domain-containing protein -
GD604_RS15120 3481649..3482035 - 387 WP_176632220.1 response regulator -
GD604_RS15125 3482213..3482416 - 204 WP_176632221.1 hypothetical protein -
GD604_RS15130 3482599..3482940 - 342 WP_176632222.1 IscA/HesB family protein -
GD604_RS15135 3483136..3483669 + 534 WP_176632223.1 bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR -
GD604_RS15140 3483697..3484197 - 501 WP_176638012.1 GNAT family N-acetyltransferase Toxin
GD604_RS15145 3484194..3484478 - 285 WP_176632225.1 DUF1778 domain-containing protein Antitoxin
GD604_RS15150 3484562..3485473 - 912 WP_176632226.1 acetylglutamate kinase -
GD604_RS15155 3485588..3486976 - 1389 WP_176632227.1 ATP-dependent protease ATPase subunit HslU -
GD604_RS15160 3487086..3487628 - 543 WP_176632228.1 ATP-dependent protease subunit HslV -
GD604_RS15165 3487640..3488206 - 567 WP_176638013.1 O-acetyl-ADP-ribose deacetylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-142)

Antitoxin

Vibrio phage ICP1, Orf50

(5-92)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 18123.86 Da        Isoelectric Point: 10.5520

>T142012 WP_176638012.1 NZ_CP045508:c3484197-3483697 [Desulfolutivibrio sulfoxidireducens]
VIRTPSPLAAEHDVVSFQSGEPVLDDWLRRRALANQASGASRTYVIADEKRVIGYYALAAGAVTATDAPGKVRRNMPDPI
PVMVLGRLAVDRDWQGRGLGFDLLRDAVLRTLRAAEIAGIRALLVHALHERAGAFYEHAGFRRSPVRPLTYVLTLADAQK
ALAFRG

Download         Length: 501 bp

>T142012 NZ_CP060281:2133250-2133352 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10679.20 Da        Isoelectric Point: 10.0050

>AT142012 WP_176632225.1 NZ_CP045508:c3484478-3484194 [Desulfolutivibrio sulfoxidireducens]
MPQANSPSRSGNINIRVALEQRNLIDQAASLCNKTRTDFILEAATKAARDAILDQVLYPVSAERFEAFQRLLDSPPEENE
RLRVLMARKPRWGK

Download         Length: 285 bp

>AT142012 NZ_CP060281:c2133359-2133214 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References