142000

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 641667..642144 Replicon chromosome
Accession NZ_CP045506
Organism Desulfolutivibrio sulfoxidireducens strain DSM 106783

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag GD605_RS02640 Protein ID WP_176629973.1
Coordinates 641667..641936 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag GD605_RS02645 Protein ID WP_176629974.1
Coordinates 641920..642144 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GD605_RS02615 637497..638054 - 558 WP_176629968.1 NapC/NirT family cytochrome c -
GD605_RS02620 638094..638993 - 900 WP_176629969.1 transposase -
GD605_RS02625 639171..640373 - 1203 WP_176629970.1 acyltransferase family protein -
GD605_RS02630 640370..641032 - 663 WP_176629971.1 CerR family C-terminal domain-containing protein -
GD605_RS02635 641389..641655 + 267 WP_176629972.1 hypothetical protein -
GD605_RS02640 641667..641936 - 270 WP_176629973.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GD605_RS02645 641920..642144 - 225 WP_176629974.1 ribbon-helix-helix domain-containing protein Antitoxin
GD605_RS02650 642507..643271 - 765 WP_176629975.1 3-hydroxyacyl-ACP dehydratase -
GD605_RS02655 643426..643599 - 174 WP_176629976.1 hypothetical protein -
GD605_RS02660 643639..643956 - 318 WP_176629977.1 TraR/DksA C4-type zinc finger protein -
GD605_RS02665 644430..644690 + 261 WP_176629978.1 hypothetical protein -
GD605_RS02670 644690..645022 + 333 WP_176629979.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Protein of unknown function DUF6290

(2-69)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10621.43 Da        Isoelectric Point: 10.3841

>T142000 WP_176629973.1 NZ_CP045506:c641936-641667 [Desulfolutivibrio sulfoxidireducens]
MNWKIEFTAEADKTLTRLGREAERRILKFMRERISKLEDPRIVGEPLKGSRFSGLWRYRAGDYRILCEIQDEKIRILVVL
VGHRGEIYK

Download         Length: 270 bp

>T142000 NZ_CP060278:2255435-2255530 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8632.83 Da        Isoelectric Point: 4.3752

>AT142000 WP_176629974.1 NZ_CP045506:c642144-641920 [Desulfolutivibrio sulfoxidireducens]
MLTIRLPAELETRLNILADTTKRPKSFYVREALERSLEDIEDVYLAEAALERFRASGEKGIPLEELERRLELED

Download         Length: 225 bp

>AT142000 NZ_CP060278:c2255615-2255558 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References