141998

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 4289492..4289975 Replicon chromosome
Accession NZ_CP045504
Organism Desulfovibrio sulfodismutans DSM 3696

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag GD606_RS19595 Protein ID WP_163300922.1
Coordinates 4289700..4289975 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag GD606_RS19590 Protein ID WP_163300921.1
Coordinates 4289492..4289716 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GD606_RS19565 4285019..4285612 + 594 WP_163300916.1 carboxymuconolactone decarboxylase family protein -
GD606_RS19570 4285609..4287336 + 1728 WP_163300917.1 thiamine pyrophosphate-binding protein -
GD606_RS19575 4287479..4287898 + 420 WP_163300918.1 VanZ family protein -
GD606_RS19580 4287935..4288729 + 795 WP_163300919.1 threonine/serine exporter family protein -
GD606_RS19585 4288729..4289193 + 465 WP_163300920.1 threonine/serine exporter family protein -
GD606_RS19590 4289492..4289716 + 225 WP_163300921.1 ribbon-helix-helix protein, CopG family Antitoxin
GD606_RS19595 4289700..4289975 + 276 WP_163300922.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GD606_RS19600 4290132..4290887 + 756 WP_163300923.1 hypothetical protein -
GD606_RS19605 4290910..4291164 + 255 WP_163300924.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
GD606_RS19610 4291303..4294071 - 2769 WP_163300925.1 excinuclease ABC subunit UvrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10575.22 Da        Isoelectric Point: 10.0905

>T141998 WP_163300922.1 NZ_CP045504:4289700-4289975 [Desulfovibrio sulfodismutans DSM 3696]
MTWAIELTPEAAKALAHLGNEAERRVVRFLRERVSRLDDPRTIGEPLKGSQFAGLWRYRAGDYRILCEIQDERVTILVVL
VGHRREVYKGR

Download         Length: 276 bp

>T141998 NZ_CP060278:c137363-137097 [Staphylococcus aureus]
ATGAGCAATTACACGGTTAAGATTAAAAATTCAGCGAAATCAGATTTAAGGAAAATAAAACATTCTTATTTAAAGAAGTC
ATTTTTAGAAATTGTTGAGACTTTAAAAAATGATCCGTATAAAATAACACAATCTTTTGAAAAATTAGAGCCTAAATATT
TAGAGCGATATTCAAGAAGAATTAACCATCAGCACAGGGTCGTCTATACCGTAGATGATCGAAATAAAGAAGTATTAATA
CTATCGGCATGGTCACATTATGATTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8471.71 Da        Isoelectric Point: 4.5463

>AT141998 WP_163300921.1 NZ_CP045504:4289492-4289716 [Desulfovibrio sulfodismutans DSM 3696]
MLTIRLPAELESRLAVLAETTKRPKSFYVREALERSLADMEDVYLAEAALERFRASGEKAVTLEEMERRLDLGD

Download         Length: 225 bp

>AT141998 NZ_CP060278:c137620-137363 [Staphylococcus aureus]
ATGATTATCACTAGCCCTACAGAAGCGAGAAAAGATTTTTATCAATTACTAAAAAATGTTAATAATAATCACGAACCAAT
TTATATTAGTGGCAATAATGCCGAAAATAATGCTGTGATTATAGGTTTAGAAGATTGGAAAAGTATACAAGAGACAATAT
ATCTTGAATCTACTGGTACAATGGACAAAGTAAGAGAAAGAGAAAAAGATAATAGTGGTACAACAAATATAGATGATATT
GATTGGGATAATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References