Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 4289492..4289975 Replicon chromosome
Accession NZ_CP045504
Organism Desulfovibrio sulfodismutans DSM 3696

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag GD606_RS19595 Protein ID WP_163300922.1
Coordinates 4289700..4289975 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag GD606_RS19590 Protein ID WP_163300921.1
Coordinates 4289492..4289716 (+) Length 75 a.a.

Genomic Context

GD606_RS19565GD606_RS19570GD606_RS19575GD606_RS19580GD606_RS19585GD606_RS19590GD606_RS19595GD606_RS19600GD606_RS19605GD606_RS19610
Location: 4285019..4285612 (594 bp)
Type: Others
Protein ID: WP_163300916.1
Location: 4285609..4287336 (1728 bp)
Type: Others
Protein ID: WP_163300917.1
Location: 4287479..4287898 (420 bp)
Type: Others
Protein ID: WP_163300918.1
Location: 4287935..4288729 (795 bp)
Type: Others
Protein ID: WP_163300919.1
Location: 4288729..4289193 (465 bp)
Type: Others
Protein ID: WP_163300920.1
Location: 4289492..4289716 (225 bp)
Type: Antitoxin
Protein ID: WP_163300921.1
Location: 4289700..4289975 (276 bp)
Type: Toxin
Protein ID: WP_163300922.1
Location: 4290132..4290887 (756 bp)
Type: Others
Protein ID: WP_163300923.1
Location: 4290910..4291164 (255 bp)
Type: Others
Protein ID: WP_163300924.1
Location: 4291303..4294071 (2769 bp)
Type: Others
Protein ID: WP_163300925.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GD606_RS195654285019..4285612+594WP_163300916.1carboxymuconolactone decarboxylase family protein-
GD606_RS195704285609..4287336+1728WP_163300917.1thiamine pyrophosphate-binding protein-
GD606_RS195754287479..4287898+420WP_163300918.1VanZ family protein-
GD606_RS195804287935..4288729+795WP_163300919.1threonine/serine exporter family protein-
GD606_RS195854288729..4289193+465WP_163300920.1threonine/serine exporter family protein-
GD606_RS195904289492..4289716+225WP_163300921.1ribbon-helix-helix protein, CopG familyAntitoxin
GD606_RS195954289700..4289975+276WP_163300922.1type II toxin-antitoxin system RelE/ParE family toxinToxin
GD606_RS196004290132..4290887+756WP_163300923.1hypothetical protein-
GD606_RS196054290910..4291164+255WP_163300924.1type II toxin-antitoxin system prevent-host-death family antitoxin-
GD606_RS196104291303..4294071-2769WP_163300925.1excinuclease ABC subunit UvrA-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10575.22 Da        Isoelectric Point: 10.0905

>T141998 WP_163300922.1 NZ_CP045504:4289700-4289975 [Desulfovibrio sulfodismutans DSM 3696]
MTWAIELTPEAAKALAHLGNEAERRVVRFLRERVSRLDDPRTIGEPLKGSQFAGLWRYRAGDYRILCEIQDERVTILVVL
VGHRREVYKGR

Download         Length: 276 bp

>T141998 NZ_CP060278:c137363-137097 [Staphylococcus aureus]
ATGAGCAATTACACGGTTAAGATTAAAAATTCAGCGAAATCAGATTTAAGGAAAATAAAACATTCTTATTTAAAGAAGTC
ATTTTTAGAAATTGTTGAGACTTTAAAAAATGATCCGTATAAAATAACACAATCTTTTGAAAAATTAGAGCCTAAATATT
TAGAGCGATATTCAAGAAGAATTAACCATCAGCACAGGGTCGTCTATACCGTAGATGATCGAAATAAAGAAGTATTAATA
CTATCGGCATGGTCACATTATGATTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8471.71 Da        Isoelectric Point: 4.5463

>AT141998 WP_163300921.1 NZ_CP045504:4289492-4289716 [Desulfovibrio sulfodismutans DSM 3696]
MLTIRLPAELESRLAVLAETTKRPKSFYVREALERSLADMEDVYLAEAALERFRASGEKAVTLEEMERRLDLGD

Download         Length: 225 bp

>AT141998 NZ_CP060278:c137620-137363 [Staphylococcus aureus]
ATGATTATCACTAGCCCTACAGAAGCGAGAAAAGATTTTTATCAATTACTAAAAAATGTTAATAATAATCACGAACCAAT
TTATATTAGTGGCAATAATGCCGAAAATAATGCTGTGATTATAGGTTTAGAAGATTGGAAAAGTATACAAGAGACAATAT
ATCTTGAATCTACTGGTACAATGGACAAAGTAAGAGAAAGAGAAAAAGATAATAGTGGTACAACAAATATAGATGATATT
GATTGGGATAATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References