Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 1874905..1875503 Replicon chromosome
Accession NZ_CP045504
Organism Desulfovibrio sulfodismutans DSM 3696

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag GD606_RS08895 Protein ID WP_163301260.1
Coordinates 1875246..1875503 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag GD606_RS08890 Protein ID WP_163301261.1
Coordinates 1874905..1875249 (-) Length 115 a.a.

Genomic Context

GD606_RS08870GD606_RS08900GD606_RS08905GD606_RS08910GD606_RS08915GD606_RS08875GD606_RS08880GD606_RS08885GD606_RS08890GD606_RS08895
Location: 1869951..1870268 (318 bp)
Type: Others
Protein ID: WP_163301264.1
Location: 1875682..1875987 (306 bp)
Type: Others
Protein ID: WP_163301274.1
Location: 1876011..1877117 (1107 bp)
Type: Others
Protein ID: WP_163301259.1
Location: 1877410..1877946 (537 bp)
Type: Others
Protein ID: WP_163301258.1
Location: 1877955..1880327 (2373 bp)
Type: Others
Protein ID: WP_163301257.1
Location: 1870442..1872367 (1926 bp)
Type: Others
Protein ID: WP_163301275.1
Location: 1872743..1873585 (843 bp)
Type: Others
Protein ID: WP_163301263.1
Location: 1873927..1874757 (831 bp)
Type: Others
Protein ID: WP_163301262.1
Location: 1874905..1875249 (345 bp)
Type: Antitoxin
Protein ID: WP_163301261.1
Location: 1875246..1875503 (258 bp)
Type: Toxin
Protein ID: WP_163301260.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GD606_RS088701869951..1870268+318WP_163301264.1ArsR family transcriptional regulator-
GD606_RS088751870442..1872367-1926WP_163301275.1TIGR03768 family metallophosphoesterase-
GD606_RS088801872743..1873585-843WP_163301263.1alpha/beta hydrolase-
GD606_RS088851873927..1874757-831WP_163301262.1cyclase family protein-
GD606_RS088901874905..1875249-345WP_163301261.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
GD606_RS088951875246..1875503-258WP_163301260.1type II toxin-antitoxin system HicA family toxinToxin
GD606_RS089001875682..1875987+306WP_163301274.1ArsR family transcriptional regulator-
GD606_RS089051876011..1877117+1107WP_163301259.1linear amide C-N hydrolase-
GD606_RS089101877410..1877946+537WP_163301258.1hypothetical protein-
GD606_RS089151877955..1880327+2373WP_163301257.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--1870442..189080420362


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(23-74)

Antitoxin

Uncharacterised protein family HicB

(54-104)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9547.20 Da        Isoelectric Point: 10.7201

>T141994 WP_163301260.1 NZ_CP045504:c1875503-1875246 [Desulfovibrio sulfodismutans DSM 3696]
MNSRLRRTLEAILAKPERGDIAWSAVEALLLALGCRKLEGDGSRVRFVSADGAILRIHRPHPRPVLDKGAVKSVRRFLCE
MEIEQ

Download         Length: 258 bp

>T141994 NZ_CP060276:4751844-4752122 [Serratia ureilytica]
GTGAAACTGATATGGACGGAACCCGCCATCGCCGATCGTCTGGCGATTTATGAATGGTTGGAACTTAAAAACCCGGCCGC
TGCCGCGGAAAATGATGTAAAAATCGCTGACGCGGCGGCACGCCTCGTGCATCATCCCGCCAGCGGAAAAACGGGTCGGA
TAGCCGGCACGCGCGAGTTGGTCATCTCTCCGTCCTATCTGCTGGTCTATGAATGGGCGGCTCAACGCGTCATCATCTTG
GCCATCGTGCATACCCGCCGCCGGTGGCCACCCGTATAG

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12588.15 Da        Isoelectric Point: 5.2157

>AT141994 WP_163301261.1 NZ_CP045504:c1875249-1874905 [Desulfovibrio sulfodismutans DSM 3696]
MNAFQYKGYLGTFEFESGDDAFHGEISGIRDVIHFTGRSVDELRLAFQEAVDDYLATCAEIGKPPEKPYSGRFMVRVSPE
IHRLAESAAKVTGKSLNAFAAETLERAAREAIKA

Download         Length: 345 bp

>AT141994 NZ_CP060276:4751557-4751826 [Serratia ureilytica]
ATGCCTGAATCTACCGTGGTAATCCGCGTGGATGAAGAGTTAAAAACCGCTTTTGCCAGCGCAGCAAAGGCCGCCGACCG
CACGGCTTCACAACTGCTGCGCGATTTCATGCGCGAGTTTGTCAGCCGCCAGGCTCAGCAGGAAGAATACGACCAGTGGC
TGAGGGAAAAAGTCGAGGTGAGCCGCAAGGCGTTGCGTGAAGGCAAGTTAGCCGACGATGAAGAGGTCGCCGCTTATTTC
GCCGAACGCAGAGCTAAATCAACGCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References