Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 3625801..3626667 Replicon chromosome
Accession NZ_CP045503
Organism Shewanella sp. YLB-08

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag FM038_RS15405 Protein ID WP_142874274.1
Coordinates 3626266..3626667 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag FM038_RS15400 Protein ID WP_142874273.1
Coordinates 3625801..3626199 (+) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FM038_RS15385 3622029..3623435 - 1407 WP_142874270.1 sulfate adenylyltransferase subunit CysN -
FM038_RS15390 3623517..3623870 - 354 WP_142874271.1 four helix bundle protein -
FM038_RS15395 3624058..3624963 - 906 WP_142874272.1 sulfate adenylyltransferase subunit CysD -
FM038_RS15400 3625801..3626199 + 399 WP_142874273.1 nucleotidyltransferase domain-containing protein Antitoxin
FM038_RS15405 3626266..3626667 + 402 WP_142874274.1 DUF86 domain-containing protein Toxin
FM038_RS15410 3627173..3627730 - 558 WP_142874275.1 hypothetical protein -
FM038_RS15415 3627896..3628228 - 333 Protein_2984 UTP--glucose-1-phosphate uridylyltransferase -
FM038_RS15420 3628268..3628468 + 201 WP_142874276.1 nucleotidyltransferase domain-containing protein -
FM038_RS15425 3628666..3629736 + 1071 WP_142874277.1 dTDP-glucose 4,6-dehydratase -
FM038_RS15430 3629733..3630608 + 876 WP_142874278.1 glucose-1-phosphate thymidylyltransferase RfbA -
FM038_RS15435 3630688..3631575 - 888 WP_142874279.1 UTP--glucose-1-phosphate uridylyltransferase GalU -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(14-129)

Antitoxin

Polymerase beta, nucleotidyltransferase

(11-96)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15110.32 Da        Isoelectric Point: 6.7496

>T141992 WP_142874274.1 NZ_CP045503:3626266-3626667 [Shewanella eurypsychrophilus]
MNDITINKLTTIRRCLTRIKDVYGDGSSFPHDYTLQDSVLLNLQRACEASIDIANHISRQHKFGVPQSSRDSFTLLAQND
VIPVALADKLKKMVGLRNIAVHDYQELNLDIVIHVIKHNLKDFEDFIDAIQPV

Download         Length: 402 bp

>T141992 NZ_CP060276:4467772-4468062 [Serratia ureilytica]
ATGATTAAATCTTTCCGCGATCGCTATCTGGAGCAGTTCTATCTGGAAGGCAGGCGCAGCCGTCTTATCCCCGGCGCGCT
CGAGCGGCAGTTGGCCAGAAAGCTCGATATGTTAGCCGCCGCGCAGCAAGAGCGTGATTTGCATCACCCCACGGGTAACT
ATTACAAGCGGCTATCCGGGCCATTTCAGGGATGGTCGAGTCTGCGCGTCAATATGCACTGGCGGCTGATGTTCCAGTGG
CGGCATGATGCCGCCGAAAAAATTTACCTCGATCCTCACCAAGATACCTGA

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14926.91 Da        Isoelectric Point: 4.3168

>AT141992 WP_142874273.1 NZ_CP045503:3625801-3626199 [Shewanella eurypsychrophilus]
MFQLDKAVLINAVRSKLPNLKLIYLFGSYASGEQHPESDLDIAILPNKALDNITRWDIAQELASEFDVDVDLIDLNCAST
VLCQQVITQGICLWGNTHDDDIFTTKTMSMYQHLQAERAEILSDFKSINHNQ

Download         Length: 399 bp

>AT141992 NZ_CP060276:4468077-4468400 [Serratia ureilytica]
ATGTTGGAAACCACGACTCGCGAACCCACCACGGTGGGAGAAGTGCTGCAGGAAGAATATTTAACGCCGTTAGGCATCGG
CCAAGAAGAACTGGCAAAGGTATTGGGCGTCACCCGCGCCACCGTCAATCGCCTGTGCAACGGGCATCGACGCATGAGCG
TTGCCGAGGCCAATCTGTTTGCCGATCTGTTCGAAACGACCGCCGACTTTTGGCTAAACCTGCAGGCGGCACACGATCGC
TGGGAAGCCAGACAGGCCGATGCGCAGCGTGTGCGGCTGCGGCCAATCAAAGAAATACTGGGACGCAATATCACTCATGC
ATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References