Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 51132..51775 Replicon plasmid unnamed3
Accession NZ_CP045499
Organism Mesorhizobium sp. INR15

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GA829_RS34440 Protein ID WP_195180250.1
Coordinates 51389..51775 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GA829_RS34435 Protein ID WP_195180249.1
Coordinates 51132..51389 (+) Length 86 a.a.

Genomic Context

GA829_RS34420GA829_RS34435GA829_RS34440GA829_RS34445GA829_RS34460GA829_RS34425GA829_RS34430GA829_RS34450GA829_RS34455GA829_RS34465
Location: 46912..48827 (1916 bp)
Type: Others
Protein ID: Protein_53
Location: 51132..51389 (258 bp)
Type: Antitoxin
Protein ID: WP_195180249.1
Location: 51389..51775 (387 bp)
Type: Toxin
Protein ID: WP_195180250.1
Location: 51772..52920 (1149 bp)
Type: Others
Protein ID: WP_195180251.1
Location: 53974..55140 (1167 bp)
Type: Others
Protein ID: WP_195180253.1
Location: 49172..49906 (735 bp)
Type: Others
Protein ID: WP_195180248.1
Location: 49912..50964 (1053 bp)
Type: Others
Protein ID: WP_195180481.1
Location: 52946..53290 (345 bp)
Type: Others
Protein ID: WP_195180252.1
Location: 53287..53625 (339 bp)
Type: Others
Protein ID: WP_195180482.1
Location: 55198..56403 (1206 bp)
Type: Others
Protein ID: WP_195180254.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GA829_RS3442046912..48827+1916Protein_53AI-2E family transporter-
GA829_RS3442549172..49906-735WP_195180248.1SMC-Scp complex subunit ScpB-
GA829_RS3443049912..50964-1053WP_195180481.1DUF1403 family protein-
GA829_RS3443551132..51389+258WP_195180249.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
GA829_RS3444051389..51775+387WP_195180250.1type II toxin-antitoxin system VapC family toxinToxin
GA829_RS3444551772..52920+1149WP_195180251.1site-specific integrase-
GA829_RS3445052946..53290-345WP_195180252.1helix-turn-helix domain-containing protein-
GA829_RS3445553287..53625-339WP_195180482.1type II toxin-antitoxin system RelE/ParE family toxin-
GA829_RS3446053974..55140+1167WP_195180253.1ATP-binding protein-
GA829_RS3446555198..56403-1206WP_195180254.1replication initiation protein RepC-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..389300389300


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(2-84)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14073.22 Da        Isoelectric Point: 4.3857

>T141989 WP_195180250.1 NZ_CP045499:51389-51775 [Mesorhizobium sp. INR15]
MVIDTSAIVAILRNEPEATTLERALVVDPVRLIPATCVLEARMVLVSRRGEHALAEIDLWLRKIEADVIPIDSELVDLAT
QAWLTYGKGRHSAALNFADCLSYALAKRADEPLLFIGNDFSQTDIEAA

Download         Length: 387 bp

>T141989 NZ_CP060276:c3296328-3295975 [Serratia ureilytica]
GTGTGGGAAATTAAAACAACGGATGCATTTGATCATTGGTTCAGATCGCTCAGCGATGCCGATCGGGCCGGTGTACTTGC
CGCATTGATGGTCCTGCGGGAAAAGGGGGCGGGGCTGCCCAGACCCTATGCCGATACGGTTAAAGGCTCACGTTACAGCA
ATATGAAAGAGTTGCGCATTCAGTGCCGAGGCGAACCGTTGCGGGCATTCTTCGCTTTCGATCCGTACTGTATTGGCATT
GTGCTTTGCGCGGGCAATAAAGCCGGTAATGAAAAGCGTTTTTACGATCGGATGATCCAGGTTGCCGATCGGGAATTCAC
GAACTGGCTGAACACATTAAACGAGAAGGAGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9600.91 Da        Isoelectric Point: 8.6588

>AT141989 WP_195180249.1 NZ_CP045499:51132-51389 [Mesorhizobium sp. INR15]
VSLNIKNPATVALADELARRQGLSKTAAIHQALSERLHRMGYSNMAQERLLGELRAIRERVARLPELDRRSDEQIIGYDE
HGIPN

Download         Length: 258 bp

>AT141989 NZ_CP060276:c3295970-3295668 [Serratia ureilytica]
ATGGGCAGAACGTTGGAACAGCTTATTGCGGATGAAAAGCCCGAGGTCGTGGCCAAAGCGCAGGCGCTGGCGGCGGACAT
CATGCTGAACATTCACCTTGCCGAGCTGCGTGAAAAAGTACAGAAAACGCAGGTTGAAATGGCGCAGGCGCTGGGGATCA
GGCAGCCGACCGTTGCCGTGATGGAAAAACCGGGCCGCGATCTGAAACTGTCTTCGCTTAAACGCTATGTTGAGGCGGCC
GGCGGCAAACTGCGCCTGGACATTGAACTGCCGGACGGCTCTCACTACGAGTTTGTGCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References