Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 280871..281658 Replicon plasmid unnamed1
Accession NZ_CP045497
Organism Mesorhizobium sp. INR15

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag GA829_RS33735 Protein ID WP_195180135.1
Coordinates 281158..281658 (+) Length 167 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag GA829_RS33730 Protein ID WP_195180134.1
Coordinates 280871..281161 (+) Length 97 a.a.

Genomic Context

GA829_RS33715GA829_RS33720GA829_RS33725GA829_RS33730GA829_RS33735GA829_RS33750GA829_RS33755GA829_RS33740GA829_RS33745GA829_RS33760GA829_RS33765
Location: 276159..277622 (1464 bp)
Type: Others
Protein ID: WP_195180131.1
Location: 277619..278644 (1026 bp)
Type: Others
Protein ID: WP_195180132.1
Location: 278683..280806 (2124 bp)
Type: Others
Protein ID: WP_195180133.1
Location: 280871..281161 (291 bp)
Type: Antitoxin
Protein ID: WP_195180134.1
Location: 281158..281658 (501 bp)
Type: Toxin
Protein ID: WP_195180135.1
Location: 284733..285413 (681 bp)
Type: Others
Protein ID: WP_195180138.1
Location: 285410..285811 (402 bp)
Type: Others
Protein ID: WP_195180139.1
Location: 281792..283708 (1917 bp)
Type: Others
Protein ID: WP_195180136.1
Location: 284026..284433 (408 bp)
Type: Others
Protein ID: WP_195180137.1
Location: 285905..286223 (319 bp)
Type: Others
Protein ID: Protein_292
Location: 286295..286618 (324 bp)
Type: Others
Protein ID: WP_195180140.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GA829_RS33715276159..277622+1464WP_195180131.1type IV secretion system protein VirB10-
GA829_RS33720277619..278644+1026WP_195180132.1P-type DNA transfer ATPase VirB11-
GA829_RS33725278683..280806+2124WP_195180133.1type IV secretory system conjugative DNA transfer family protein-
GA829_RS33730280871..281161+291WP_195180134.1DUF1778 domain-containing proteinAntitoxin
GA829_RS33735281158..281658+501WP_195180135.1GNAT family N-acetyltransferaseToxin
GA829_RS33740281792..283708-1917WP_195180136.1relaxase/mobilization nuclease domain-containing protein-
GA829_RS33745284026..284433-408WP_195180137.1hypothetical protein-
GA829_RS33750284733..285413+681WP_195180138.1ParA family protein-
GA829_RS33755285410..285811+402WP_195180139.1hypothetical protein-
GA829_RS33760285905..286223-319Protein_292hypothetical protein-
GA829_RS33765286295..286618-324WP_195180140.1DUF736 family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..305508305508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(67-144)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 17890.62 Da        Isoelectric Point: 9.6531

>T141988 WP_195180135.1 NZ_CP045497:281158-281658 [Mesorhizobium sp. INR15]
MSVAAPEPLTAHHDIQSFMSGVESLDHWLKHRALKNQTTGASRTFVACDGRRGLAYYALASSAITVDAAPGRFRRNMPDP
IPVVILGRLAVDQSRQGSGFGRALVRDAGLRVIQAADTIGIRGMIVHALSEEAKAFYMRTGFEPSPLDPMTLMVTLADLK
ASLSLT

Download         Length: 501 bp

>T141988 NZ_CP060276:1984115-1984211 [Serratia ureilytica]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10806.36 Da        Isoelectric Point: 8.6352

>AT141988 WP_195180134.1 NZ_CP045497:280871-281161 [Mesorhizobium sp. INR15]
MATLSTPQNKRETLNIRIKPEERSLIDRAAKARGKNRTDFVLEAARMAAEEALLDQAVIAANPEAYAAFLARLDMPPEPN
ERLRETMRTSAPWEKA

Download         Length: 291 bp

>AT141988 NZ_CP060276:c1984211-1984071 [Serratia ureilytica]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References