Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-VagC
Location 3469535..3470202 Replicon chromosome
Accession NZ_CP045496
Organism Mesorhizobium sp. INR15

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GA829_RS16960 Protein ID WP_210337672.1
Coordinates 3469807..3470202 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GA829_RS16955 Protein ID WP_195173863.1
Coordinates 3469535..3469807 (+) Length 91 a.a.

Genomic Context

GA829_RS16930GA829_RS16935GA829_RS16955GA829_RS16960GA829_RS16940GA829_RS16945GA829_RS16950GA829_RS16965GA829_RS16970GA829_RS16975GA829_RS16980GA829_RS16985
Location: 3464872..3465858 (987 bp)
Type: Others
Protein ID: WP_195173860.1
Location: 3465930..3466409 (480 bp)
Type: Others
Protein ID: WP_195179700.1
Location: 3469535..3469807 (273 bp)
Type: Antitoxin
Protein ID: WP_195173863.1
Location: 3469807..3470202 (396 bp)
Type: Toxin
Protein ID: WP_210337672.1
Location: 3466404..3467552 (1149 bp)
Type: Others
Protein ID: WP_195173861.1
Location: 3467621..3468070 (450 bp)
Type: Others
Protein ID: WP_006202816.1
Location: 3468325..3469311 (987 bp)
Type: Others
Protein ID: WP_195173862.1
Location: 3470233..3471273 (1041 bp)
Type: Others
Protein ID: WP_195173865.1
Location: 3471286..3472170 (885 bp)
Type: Others
Protein ID: WP_195173866.1
Location: 3472163..3473014 (852 bp)
Type: Others
Protein ID: WP_195173867.1
Location: 3473031..3474062 (1032 bp)
Type: Others
Protein ID: WP_195173868.1
Location: 3474305..3475027 (723 bp)
Type: Others
Protein ID: WP_195173869.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GA829_RS169303464872..3465858+987WP_195173860.1ABC transporter permease-
GA829_RS169353465930..3466409+480WP_195179700.1gluconokinase-
GA829_RS169403466404..3467552-1149WP_195173861.1hypothetical protein-
GA829_RS169453467621..3468070-450WP_006202816.1Rrf2 family transcriptional regulator-
GA829_RS169503468325..3469311-987WP_195173862.1sulfate ABC transporter substrate-binding protein-
GA829_RS169553469535..3469807+273WP_195173863.1antitoxinAntitoxin
GA829_RS169603469807..3470202+396WP_210337672.1type II toxin-antitoxin system VapC family toxinToxin
GA829_RS169653470233..3471273-1041WP_195173865.1sulfate/molybdate ABC transporter ATP-binding protein-
GA829_RS169703471286..3472170-885WP_195173866.1sulfate ABC transporter permease subunit CysW-
GA829_RS169753472163..3473014-852WP_195173867.1sulfate ABC transporter permease subunit CysT-
GA829_RS169803473031..3474062-1032WP_195173868.1sulfate ABC transporter substrate-binding protein-
GA829_RS169853474305..3475027-723WP_195173869.1M15 family metallopeptidase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-116)

Antitoxin

SpoVT-AbrB domain

(17-55)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14000.20 Da        Isoelectric Point: 5.1469

>T141987 WP_210337672.1 NZ_CP045496:3469807-3470202 [Mesorhizobium sp. INR15]
MRFMLDTSIISDMIRNPAGNAASAMAREGDDAVCTSIVVASELRYGCAKKGSAKLLSKVEQLLAEIPVLPLDVPVDAEYG
AIRAELEGAGQAIGHNLFIAAHAYVLGITLVTANWGEFTRIRGLKVENWLA

Download         Length: 396 bp

>T141987 NZ_CP060276:c1712770-1712486 [Serratia ureilytica]
ATGACTTATAAGCTTGAATTCGAAGAACATGCGCTGAAGGAATTTAAAAAACTGTCCCCGGTGATCCGGGAACAGTTCAA
AAAAAAGCTGGCATCGGTGCTGGTTAATCCCCACGTCCCCGCCAACAAACTCGCCGGTTTGCCCGATTGCTACAAAATCA
AACTCAGAGCCTCAGGCTTTCGTTTGGTATATCGCGTCATGGAAACGGAGATCGTGGTTCTGGTCCTGTCTGTGGGCAAA
CGCGAACGTTCAGCGGCTTACACCGCTGCCAAAAAGCGCCTTTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10133.56 Da        Isoelectric Point: 5.6343

>AT141987 WP_195173863.1 NZ_CP045496:3469535-3469807 [Mesorhizobium sp. INR15]
MPQHRHSTTLPKEAKLFRNNRSQAVRIPVEFELPGDKVLISREGDRLVIEAVRKPGLTALLSQWAKEAPLGPEDDFPEIG
DAPIHPEDIF

Download         Length: 273 bp

>AT141987 NZ_CP060276:c1713011-1712760 [Serratia ureilytica]
ATGACGGTTCAACCCATTCTTGCCGACTCGGCTGTCAGCATCAGCGATTTTAAGAAATCGCCCAACGCCGCCCTTAAAGA
GGCACAAGGGCAACCGGTCGCCGTCCTGACCAACGGTAAGATTTCGGGATATTACGTCTCTCCGGAAACCTGGGAGGCGA
TCGCGGAATACCTGGAAGATATCGAACTCGCTGAAATCGTTCGTTCACGGATGAACGGCAAACGCATTAAGGTCAATTTG
GATGACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References