Detailed information of TA system TA141985

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): shpAB/BrnT-BrnA
• Location: 1450125..1450680
• Replicon: chromosome
• Accession: NZ_CP045496
• Organism: Mesorhizobium sp. INR15

Toxin (Protein)

• Gene name: shpA
• Uniprot ID: -
• Locus tag: GA829_RS06940
• Protein ID: WP_195177801.1
• Coordinates: 1450125..1450412 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: shpB
• Uniprot ID: -
• Locus tag: GA829_RS06945
• Protein ID: WP_195177802.1
• Coordinates: 1450393..1450680 (+)
• Length: 96 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GA829_RS06910	1446024..1446863	-	840	WP_195177796.1	MoxR family ATPase	-
GA829_RS06915	1447024..1447458	+	435	WP_195177797.1	DUF4345 domain-containing protein	-
GA829_RS06925	1447738..1448325	+	588	WP_195177798.1	5-formyltetrahydrofolate cyclo-ligase	-
GA829_RS06930	1448380..1449204	+	825	WP_195177799.1	YmdB family metallophosphoesterase	-
GA829_RS06935	1449281..1450045	+	765	WP_195177800.1	TerC family protein	-
GA829_RS06940	1450125..1450412	+	288	WP_195177801.1	BrnT family toxin	Toxin
GA829_RS06945	1450393..1450680	+	288	WP_195177802.1	BrnA antitoxin family protein	Antitoxin
GA829_RS06950	1450685..1451152	-	468	WP_195177803.1	SRPBCC family protein	-
GA829_RS06955	1451176..1451538	-	363	WP_195177804.1	hypothetical protein	-
GA829_RS06960	1451563..1452045	-	483	WP_195177805.1	SRPBCC domain-containing protein	-
GA829_RS06965	1452097..1452420	+	324	WP_195177806.1	helix-turn-helix domain-containing protein	-
GA829_RS06970	1452646..1453395	+	750	WP_195177807.1	YebC/PmpR family DNA-binding transcriptional regulator	-
GA829_RS06975	1453392..1453718	+	327	WP_195177808.1	SelT/SelW/SelH family protein	-
GA829_RS06980	1453870..1454349	-	480	WP_195177809.1	DUF1772 domain-containing protein	-
GA829_RS06985	1454351..1455184	-	834	WP_195177810.1	NAD(P)H-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-86)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (29-86)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11183.65 Da
• Isoelectric Point: 6.3327

>T141985 WP_195177801.1 NZ_CP045496:1450125-1450412 [Mesorhizobium sp. INR15]
MQFDWDPEKARRNLAKHGITFDLARKVFDDPLHLIVPDRLEDGEQRWHAIGMVEAIVVLLVVHAYPDRDDEDRVRIVGAR
KATSHERRRYEQEAP

Nucleotide

• Length: 288 bp

>T141985 NZ_CP060276:c1093334-1093131 [Serratia ureilytica]
ATGACTAAAACCGACTATCTGATGCGTTTACGTAAATGCACCACGATTGATACTCTCGAACGTGTTATTGAAAAAAATAA
GTACGAGCTTTCCGATGATGAACTGGAGCTGTTTTACTCAGCCGCCGATCATCGTTTGGCGGAGCTGACCATGAACAAGC
TGTATGACAAAATCCCCACCTCCGTTTGGAAATATGTCAGATAA

Antitoxin

Protein

• Length: 96 a.a.
• Molecular weight: 11076.43 Da
• Isoelectric Point: 6.9904

>AT141985 WP_195177802.1 NZ_CP045496:1450393-1450680 [Mesorhizobium sp. INR15]
MNRKPLSEDQRDQLAKLADLPDSEIDTSDIPEAPTENWIHARRGHLYRPLKQPVTIRLDADVLSWFKEHVGGGGYQTEIN
RVLRHHVIEQEKRRS

Nucleotide

• Length: 288 bp

>AT141985 NZ_CP060276:c1093753-1093385 [Serratia ureilytica]
ATGGATGAGTATTCGCCTAAGCGACACGACATTGCTCAACTCAAATTCTTGTGCGAAAATTTGTATGATGAAGGTATCGC
CACCCTGGGAGACAGCCACCACGGGTGGGTCAACGATCCGACATCCTCCGTCAACCTTCAGCTTAATGAGTTGATCGAAC
ATATCGCTTCGTTTGTGATGAGTTATAAAATTAAATACATGGACGAATCCGATTTGTCGGAGTTAGTCGAGGAATATCTC
GACGATACCTATACGCTGTTCAGCAGCTACGGTATCAATGATTCCGACCTGCGCCGCTGGCAAAAAACCAAGGCGAGATT
ATTCAGAATGTTCTCAGGAGAGGACATCTGTACGACAATGAAAACTTAG