Detailed information of TA system TA141931

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 477956..478472
• Replicon: chromosome
• Accession: NZ_CP045485
• Organism: Enterobacter cloacae strain 88701

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: GEA56_RS02340
• Protein ID: WP_041911453.1
• Coordinates: 478188..478472 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A8E1RL94
• Locus tag: GEA56_RS02335
• Protein ID: WP_023331889.1
• Coordinates: 477956..478198 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GEA56_RS02320	473991..474731	+	741	WP_203464058.1	KDGP aldolase family protein	-
GEA56_RS02325	474812..475948	+	1137	WP_203464059.1	lactonase family protein	-
GEA56_RS02330	475968..477878	+	1911	WP_102750468.1	BglG family transcription antiterminator	-
GEA56_RS02335	477956..478198	+	243	WP_023331889.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
GEA56_RS02340	478188..478472	+	285	WP_041911453.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
GEA56_RS02345	478476..478940	-	465	WP_063450879.1	anaerobic ribonucleoside-triphosphate reductase-activating protein	-
GEA56_RS02350	479026..481164	-	2139	WP_203464060.1	anaerobic ribonucleoside-triphosphate reductase	-
GEA56_RS02355	481533..482105	-	573	WP_203464061.1	fructose PTS transporter subunit IIA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-83)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-69)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11001.95 Da
• Isoelectric Point: 10.0526

>T141931 WP_041911453.1 NZ_CP045485:478188-478472 [Enterobacter cloacae]
MIYELEFDPRALKEWHKLGDTVKCQFKKKLADVLVNPRIESARLHGLPDCYKIKLRSLGYRLVYQVQDNVVTVFVIAIGK
REKSAVYHEANKRL

Nucleotide

• Length: 285 bp

>T141931 NZ_CP060241:c2803150-2802572 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTGTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTCCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAGGCCGCGCACCCGGACAAAGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCACCTCGACGC
GCCGCTGCGCGACCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAAGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCAGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9030.41 Da
• Isoelectric Point: 4.7719

>AT141931 WP_023331889.1 NZ_CP045485:477956-478198 [Enterobacter cloacae]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTISDSEDELIQTVRERLANPQKGIKVSLDDL

Nucleotide

• Length: 243 bp

>AT141931 NZ_CP060241:c2803793-2803239 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTCCCTTCTTCGTCCCTGGGCCCCGCCCTGCGTCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCGCGCTGGGAATCCGGTACCCAGGCGCTGCTGGTGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAGCCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCCTGTTGGCCTGTTCGCCGGCACGCGCCGCGCAATTCGGCGT
GCCTCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACGCCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTGCGCCTGGTGGAAACCCTCTGA