Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relE/YoeB-RelB
Location 3206836..3207347 Replicon chromosome
Accession NZ_CP045456
Organism Brevundimonas sp. Bb-A

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag BSP_RS15840 Protein ID WP_152950968.1
Coordinates 3206836..3207096 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag BSP_RS15845 Protein ID WP_152951182.1
Coordinates 3207093..3207347 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSP_RS15825 3204697..3205083 + 387 WP_054766656.1 DUF983 domain-containing protein -
BSP_RS15830 3205108..3205467 - 360 WP_152950967.1 hypothetical protein -
BSP_RS15835 3205464..3206762 - 1299 WP_194166983.1 homogentisate 1,2-dioxygenase -
BSP_RS15840 3206836..3207096 - 261 WP_152950968.1 Txe/YoeB family addiction module toxin Toxin
BSP_RS15845 3207093..3207347 - 255 WP_152951182.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BSP_RS15850 3207396..3208559 - 1164 WP_152950969.1 acyl-CoA dehydrogenase family protein -
BSP_RS15855 3208799..3210583 - 1785 WP_152950970.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -
BSP_RS15860 3210587..3211069 - 483 WP_054766660.1 MerR family DNA-binding transcriptional regulator -
BSP_RS15865 3211251..3211667 - 417 WP_152950971.1 DoxX family protein -
BSP_RS15870 3211849..3212070 - 222 WP_152950972.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10289.75 Da        Isoelectric Point: 9.0275

>T141857 WP_152950968.1 NZ_CP045456:c3207096-3206836 [Brevundimonas sp. Bb-A]
MRLTFQEAAWEDYLYWQSTDTKQLKKINGLIRECLRTPFSGTGKPEPLKGELSGWWSRRIDQEHRLVYRPTEDALLIAQC
RYHYAK

Download         Length: 261 bp

>T141857 NZ_CP060122:c4508521-4508252 [Sphingobium yanoikuyae]
ATGGCAGTCGAAACGCATCCGGATAGCTGGACGGTAGCACAGGCCAAGGCGCGCCTGAGCGAGGTAATCGAGAAGGCGCG
GCGCGAGCCCCAGGCGATTACGCGTCACGGCAAAAGCGCCGTCGTCGTGGTCGATGCCGAACTATGGGAACGGGTTCAAC
GTCGCCAGCATCGCGGCAGCTTCGCCGACTTCCTGCTGACCTCGCCGTTGCGCGGATCGGGTCTTGAGGTCGATCGCCTC
AAGGATGGTGTTCGCGAGATTGATCTATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9232.43 Da        Isoelectric Point: 4.7824

>AT141857 WP_152951182.1 NZ_CP045456:c3207347-3207093 [Brevundimonas sp. Bb-A]
MKAMSVTELRKNLASAIDRVTADHDYTIITRDGGKPAAVLMSLEDFASWQETDYLLRSPANAERLRKAVAELDAGGGQPR
DLIE

Download         Length: 255 bp

>AT141857 NZ_CP060122:c4508255-4507824 [Sphingobium yanoikuyae]
ATGAGTTTCCTGCTCGATACCAACATCATCTCGGAGGGAGCAAAGCCGCGTCCTGATCCCGGCGTGATGGATTGGCTGGC
GTCGGTGGATGAGGAAGAGCTGTTCCTGAGCGTGGTATCGCTGGCAGAACTGCGCCACGGCATTGAGCGCATGGACAAGG
GGGCACGACAGTCGGGCCTCGACATCTGGCTGACCGAACAACTGGCGCCGCGATTTGAGGAAAGACTGCTCTCCATCGAC
AGCGTAACGGCGGATCTGTGGGGCCGTATTGTCAATCGAGCACAAGGCGCGGGCCGCCCCATGGGAGCGATGGATGCTTT
CATCGCCGCCCATGCGCAGCAGCACGAACTCACACTCGTGACCCGCAATATTTCCGACTTCGAGGCGACTGGTATCCGCC
TGTTCAACCCATGGACCGAAGGGAAAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References